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    Anxiety disorder and eating habits in adolescents with gastroesophageal reflux disease
    (Dr Behcet Uz Cocuk Hastaliklari Ve Cerrahisi, 2018) Ozbeyler, Omer; Eliacik, Kayi; Uzum, Ozlem; Kanik, Ali; Cagan Appak, Yeliz; Karakoyun, Miray; Orbatu, Dilek; Engin Ozyurt, Gonca; Bolat, Nurullah; Baran, Masallah
    Objective: It was aimed to evaluate the relationship between eating habits and reflux by investigating eating habits in adolescent patients with gastroesophageal reflux disease, and also to assess the interplay between gastroesophageal reflux disease and anxiety. Methods: We included patients between the ages of 12 and 18 diagnosed as gastroesophageal reflux disease in the pediatric gastroenterology outpatient clinic but who had not yet been treated. The control group consisted of age matched adolescents who applied for upper respiratory tract infection. The relationship between eating habits and reflux was assessed with Adolescent Nutrition Checklist, and relationship between gastroesophageal reflux disease and anxiety was assessed with Anxiety Disorder Screening Questionnaire. Results: Seventy adolescents with reflux disease and 67 adolescents as the control group were included in the study. There was no significant difference between the groups regarding the eating habits and anxiety scores. However, it was seen that most of the patients in both groups. had poor eating habits and higher general anxiety score. Conclusion: No relation was found between the gastroesophageal reflux disease, anxiety and eating habits in adolescents. These results suggested that reflux disease should be separated from other gastrointestinal complaints such as abdominal pain which may be psychosomatic. However, there was a quantitative increment in poor eating habits in those with gastroesophageal reflux disease. For this reason there is a need for further studies which investigate the eating habits with a larger sample size of this population.
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    Brain natriuretic peptide: the reason of respiratory distress is heart disease or lung disease?
    (W B Saunders Co-Elsevier Inc, 2015) Sahingozlu, Taylan; Karadas, Ulas; Eliacik, Kayi; Bakiler, Ali Rahmi; Karadas, Nihal Ozdemir; Kanik, Muhammed Ali; Baran, Masaallah
    Objectives: The aim of this study was to determine whether plasma levels of amino-terminal brain natriuretic peptide (BNP) could differentiate between heart failure and lung disease among infants with acute bronchiolitis. Methods: Sixty-eight infants (age range, 1-26 months; median age, 5.9 +/- 5.0 months) who presented with respiratory distress underwent physical examination, plasma BNP measurement, and echocardiography within 24 hours after admission. Nineteen (28%) patients had congenital heart disease. The control group was consisted of 30 healthy infants. Results: Although mean plasma BNP levels were 118.9 +/- 219.5 pg/mL in patients with isolated bronchiolitis (n = 49), it was 841.2 +/- 1475.8 pg/mL in patients with congenital heart disease (n = 19). Plasma BNP levels were significantly higher in infants with congenital heart disease (P = .001). Conclusion: It was shown that plasma BNP levels were affected much more in cardiac disease rather than lung disease. Among infants with respiratory distress, plasma BNP measurements can differentiate congenital heart disease and lung disease and can be used to monitor the effects of treatment for infants with heart failure. Response to reviewers: The comments were taken for consideration. The patient groups control BNP levels were attached to the results. As it was a clinical study and multiple factors (respiratory score, respiratory rate, treatment, etc) may effect on BNP levels, the tables could not be decreased to 1 table. (C) 2015 Elsevier Inc. All rights reserved.
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    Brain natriuretic peptide: the reason of respiratory distress is heart disease or lung disease?
    (W B Saunders Co-Elsevier Inc, 2015) Sahingozlu, Taylan; Karadas, Ulas; Eliacik, Kayi; Bakiler, Ali Rahmi; Karadas, Nihal Ozdemir; Kanik, Muhammed Ali; Baran, Masaallah
    Objectives: The aim of this study was to determine whether plasma levels of amino-terminal brain natriuretic peptide (BNP) could differentiate between heart failure and lung disease among infants with acute bronchiolitis. Methods: Sixty-eight infants (age range, 1-26 months; median age, 5.9 +/- 5.0 months) who presented with respiratory distress underwent physical examination, plasma BNP measurement, and echocardiography within 24 hours after admission. Nineteen (28%) patients had congenital heart disease. The control group was consisted of 30 healthy infants. Results: Although mean plasma BNP levels were 118.9 +/- 219.5 pg/mL in patients with isolated bronchiolitis (n = 49), it was 841.2 +/- 1475.8 pg/mL in patients with congenital heart disease (n = 19). Plasma BNP levels were significantly higher in infants with congenital heart disease (P = .001). Conclusion: It was shown that plasma BNP levels were affected much more in cardiac disease rather than lung disease. Among infants with respiratory distress, plasma BNP measurements can differentiate congenital heart disease and lung disease and can be used to monitor the effects of treatment for infants with heart failure. Response to reviewers: The comments were taken for consideration. The patient groups control BNP levels were attached to the results. As it was a clinical study and multiple factors (respiratory score, respiratory rate, treatment, etc) may effect on BNP levels, the tables could not be decreased to 1 table. (C) 2015 Elsevier Inc. All rights reserved.
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    Brain natriuretic peptide: the reason of respiratory distress is heart disease or lung disease?
    (W B Saunders Co-Elsevier Inc, 2015) Sahingozlu, Taylan; Karadas, Ulas; Eliacik, Kayi; Bakiler, Ali Rahmi; Karadas, Nihal Ozdemir; Kanik, Muhammed Ali; Baran, Masaallah
    Objectives: The aim of this study was to determine whether plasma levels of amino-terminal brain natriuretic peptide (BNP) could differentiate between heart failure and lung disease among infants with acute bronchiolitis. Methods: Sixty-eight infants (age range, 1-26 months; median age, 5.9 +/- 5.0 months) who presented with respiratory distress underwent physical examination, plasma BNP measurement, and echocardiography within 24 hours after admission. Nineteen (28%) patients had congenital heart disease. The control group was consisted of 30 healthy infants. Results: Although mean plasma BNP levels were 118.9 +/- 219.5 pg/mL in patients with isolated bronchiolitis (n = 49), it was 841.2 +/- 1475.8 pg/mL in patients with congenital heart disease (n = 19). Plasma BNP levels were significantly higher in infants with congenital heart disease (P = .001). Conclusion: It was shown that plasma BNP levels were affected much more in cardiac disease rather than lung disease. Among infants with respiratory distress, plasma BNP measurements can differentiate congenital heart disease and lung disease and can be used to monitor the effects of treatment for infants with heart failure. Response to reviewers: The comments were taken for consideration. The patient groups control BNP levels were attached to the results. As it was a clinical study and multiple factors (respiratory score, respiratory rate, treatment, etc) may effect on BNP levels, the tables could not be decreased to 1 table. (C) 2015 Elsevier Inc. All rights reserved.
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    The subclinical effect of celiac disease on the heart and the effect of gluten-free diet on cardiac functions
    (Turkish J Pediatrics, 2016) Karadas, Ulas; Eliacik, Kayi; Baran, Masallah; Kanik, Ali; Ozdemir, Nihal; Ince, Osman Tolga; Bakiler, Ali Rahmi
    This study aimed to investigate the effects of celiac disease (CD) on cardiac function in children by using conventional transthoracic echocardiography (TTE) and tissue Doppler echocardiography (TDE). Forty-nine patients diagnosed with CD were enrolled into the study. Group 1 consisted of 26 (53%) patients who had recently been diagnosed and had not been on glutenfree diet whereas Group 2 consisted of 23 (47%) patients who had been on regular gluten-free diet for at least 10 months. 20 healthy children were enrolled into the study as the control group. The deceleration time (DT) and the left ventricle (LV) isovolumetric relaxation time (IVRT) were significantly shorter in Group 1 compared to Group 2 and the control group (p=0.002, p=0.015). Mitral valve E/E' ratio was significantly lower in Group 1 and 2 when compared to the control group (p<0.001). The study demonstrated that evaluation of these parameters by using TDE could be beneficial in the early diagnosis of cardiac involvement in children with CD.