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    Pseudo-Bartter Syndrome in Patients with Cystic Fibrosis and Clinical Features
    (Galenos Publ House, 2023) Ozaslan, Mehmet Mustafa; Senol, Handan Duman; Barlık, Meral; Coksuer, Fevziye; Dindar, Bahar; Demir, Esen; Gülen, Figen
    Objective: Pseudo-Bartter syndrome (PBS) is a complication of cystic fibrosis (CF) accompanied by electrolyte disorders. We aimed to compare the clinical features of patients diagnosed with CF with or without PBS in our clinic.Method: One hundred twenty-eight patients with the diagnosis CF data was recorded. Clinical features, diagnostic test results, colonization status, complications and genetic test results were compared in patients with and without PBS.Results: Totally 128 patients who were regularly followed diagnosis CF January 2017 and May 2022 and 18 of them (14%) developed PBS. Median age of CF diagnosis was significantly lower in patients with PBS (p<0.003). There was a significant difference between the two groups in terms of colonization. In the group with PBS, the chronic respiratory tract colonization was detected more. There were no significant differences for age, gender, weight, height, sweat test. The most common genetic mutation was c1521_1523delCTT (p. F508Del).Conclusion: PBS was the most common finding in our patients with CF. It may be exacerbated by the warm weather conditions in our country. It may be a clue for early diagnosis of CF.