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Öğe Celiac Disease Screening on Students of the Department of Nutrition and Dietetics and Medical School at Ege University(Galenos Yayincilik, 2015) Karakoyun, Miray; Deviren, Recep; Ozturk, Ozan; Genc, Rabia Etki; Aydogdu, SemaAim: Celiac disease is an autoimmune enteropathy which improves in genetic predisposition circumstances. Silent and atypical forms cause diagnostic problems. In this study; we aimed to improve the awareness by applying the finger prick test to the students studying in two different departments at Ege University. Materials and Methods: We included 143 of the 173 students from Ataturk School of Health, Department of Nutrition and Dietetics in this study and 359 5th grade students in the Faculty of Medicine who were selected randomly during their practical lesson. Biocard finger prick test was applied to a total of 502 students. Students with positive results were further examined based on ESPGHAN 2012 diagnosis criteria. Results: Of the 502 students, 259 were females (51.5%) and 243 were males (49.5%). The age range was 17-24 years. Finger prick test was positive in 1 female student from the department of nutrition and dietetics (1/143), and in 3 male students from the faculty of medicine (3/359). These four students had anemia and the others were asymptomatic. One of the asymptomatic students was overweight. Routine hematological, biochemical and serological tests were performed in these four students. None of them presented isolated IgA deficiency. Anti-tissue transglutaminase, anti-gliadin and anti-endomysial antibodies were positive. Duodenal endoscopy revealed mucosal damage in these four students. Histopathological examinations were found to be compatible with Marsh 3 celiac disease. All patients were started on a gluten free diet. Conclusion: In this study, after the screening test during routine practice, we found a prevalence of celiac disease of 0.8% among students of two different departments at Ege University. Of the students, 50% were asymptomatic and this finding drew attention to the silent form of the disease.Öğe Celiac Disease Screening on Students of the Department of Nutrition and Dietetics and Medical School at Ege University(Galenos Yayincilik, 2015) Karakoyun, Miray; Deviren, Recep; Ozturk, Ozan; Genc, Rabia Etki; Aydogdu, SemaAim: Celiac disease is an autoimmune enteropathy which improves in genetic predisposition circumstances. Silent and atypical forms cause diagnostic problems. In this study; we aimed to improve the awareness by applying the finger prick test to the students studying in two different departments at Ege University. Materials and Methods: We included 143 of the 173 students from Ataturk School of Health, Department of Nutrition and Dietetics in this study and 359 5th grade students in the Faculty of Medicine who were selected randomly during their practical lesson. Biocard finger prick test was applied to a total of 502 students. Students with positive results were further examined based on ESPGHAN 2012 diagnosis criteria. Results: Of the 502 students, 259 were females (51.5%) and 243 were males (49.5%). The age range was 17-24 years. Finger prick test was positive in 1 female student from the department of nutrition and dietetics (1/143), and in 3 male students from the faculty of medicine (3/359). These four students had anemia and the others were asymptomatic. One of the asymptomatic students was overweight. Routine hematological, biochemical and serological tests were performed in these four students. None of them presented isolated IgA deficiency. Anti-tissue transglutaminase, anti-gliadin and anti-endomysial antibodies were positive. Duodenal endoscopy revealed mucosal damage in these four students. Histopathological examinations were found to be compatible with Marsh 3 celiac disease. All patients were started on a gluten free diet. Conclusion: In this study, after the screening test during routine practice, we found a prevalence of celiac disease of 0.8% among students of two different departments at Ege University. Of the students, 50% were asymptomatic and this finding drew attention to the silent form of the disease.Öğe Celiac Disease Screening on Students of the Department of Nutrition and Dietetics and Medical School at Ege University(Galenos Yayincilik, 2015) Karakoyun, Miray; Deviren, Recep; Ozturk, Ozan; Genc, Rabia Etki; Aydogdu, SemaAim: Celiac disease is an autoimmune enteropathy which improves in genetic predisposition circumstances. Silent and atypical forms cause diagnostic problems. In this study; we aimed to improve the awareness by applying the finger prick test to the students studying in two different departments at Ege University. Materials and Methods: We included 143 of the 173 students from Ataturk School of Health, Department of Nutrition and Dietetics in this study and 359 5th grade students in the Faculty of Medicine who were selected randomly during their practical lesson. Biocard finger prick test was applied to a total of 502 students. Students with positive results were further examined based on ESPGHAN 2012 diagnosis criteria. Results: Of the 502 students, 259 were females (51.5%) and 243 were males (49.5%). The age range was 17-24 years. Finger prick test was positive in 1 female student from the department of nutrition and dietetics (1/143), and in 3 male students from the faculty of medicine (3/359). These four students had anemia and the others were asymptomatic. One of the asymptomatic students was overweight. Routine hematological, biochemical and serological tests were performed in these four students. None of them presented isolated IgA deficiency. Anti-tissue transglutaminase, anti-gliadin and anti-endomysial antibodies were positive. Duodenal endoscopy revealed mucosal damage in these four students. Histopathological examinations were found to be compatible with Marsh 3 celiac disease. All patients were started on a gluten free diet. Conclusion: In this study, after the screening test during routine practice, we found a prevalence of celiac disease of 0.8% among students of two different departments at Ege University. Of the students, 50% were asymptomatic and this finding drew attention to the silent form of the disease.Öğe Çocuklarda kronik öksürük nedenlerinin retrospektif değerlendirilmesi(Ege Üniversitesi, Tıp Fakültesi, 2016) Deviren, Recep; Tanaç, RemziyeAmaç: Bu çalışmadaki amacımız EÜTF Çocuk Solunum ve Allerji Polikliniği'ne 2011-2014 yıllarında kronik öksürük nedeni ile başvuran ve takip edilen olguların, kronik öksürük etyolojilerini değerlendirmek ve kronik öksürük tedavisine katkıda bulunmaktır. Materyal ve Metod: Bu çalışma Ocak 2011 - Aralık 2014 tarihleri arasında Ege Üniversitesi Tıp Fakültesi Çocuk Hastanesi, Çocuk Solunum ve Allerji Polikliniğine kronik öksürük yakınması ile başvuran 18 yaş altı çocuklar üzerinde retrospektif olarak gerçekleştirilmiştir. Hastaların dosyalarından ayrıntılı anamnezleri, öksürük süreleri, öksürük karakterleri, spesifik öksürük semptom ve fizik muayene bulguları, öksürüğü tetikleyici faktör varlığı, aile özellikleri, öz-soy geçmiş, laboratuvar tetkik ve sonuçları, görüntüleme yöntemleri ve tedavileri kaydedildi. Bulgular: Çalışmaya 201 hasta dahil edildi. Hastaların yaşları 6 ay ile 17 yaş arasında değişmekte olup ortalaması 6,28±3,80 yaş olarak saptandı. Hastaların 125'i (%62,2) erkek, 76'sı (%37,8) kız olarak saptandı. Olgularımızın 21'i (%10,4) 0-2 yaş arasında, 78'i (%38,8) 2-6 yaş arasında, 102'si (%50,7) ise 6 yaşından büyük olarak saptandı. Cinsiyet ile yaş grupları arasında istatistiksel olarak bir fark saptanmadı (p=0,166). Hastaların başvuru sırasında ortalama öksürük süresi 9,21±5,96 hafta arasında değişmekteydi (4-24 hafta). Hastaların öksürük süreleri bakımından yaş grupları arasında istatistiksel olarak bir fark saptanmadı (p=0,173). Toplam 201 hastanın 66'sında (%32,8) Üst Havayolu Öksürük Sendromu, 55'inde (%27,4) Astım/Astım Benzeri Semptom, 30'unda (%14,9) Persistan Bakteriyel Bronşit ve 10'unda (%5,0) Gastroözefageal Reflü Hastalığı en sık görülen tanılar olarak saptandı. Çalışmaya alınan 201 hastanın almış oldukları tanılar yaş gruplarına göre sınıflandırıldığında 0-2 yaş grubunda en sık görülen tanı 7 (%33,3) hasta ile GÖRH, 2-6 yaş grubunda 23 (%29,5) hasta ile Astım/Astım Benzeri Semptom, 6 yaş üzerindeki grupta ise 49 (%48) hasta ile Üst Havayolu Öksürük Sendromu olarak tespit edildi. Sonuç: Sonuç olarak çalışmamızda kronik öksürük nedenleri literatürde yer alan hem yabancı hem de ülkemizde yapılan çalışmalar ile karşılaştırıldığında, benzerlikler olduğu kadar bazı önemli farklılıklar da içermektedir. Bizim çalışmamızda kronik öksürüğün en sık nedeni 0-2 yaş grubunda GÖRH, 2-6 yaş grubunda Astım/Astım Benzeri Semptom, >6 yaş grubunda ise ÜHÖS olarak saptanmıştır. Bunun nedeni hem olgu sayımızın az olması, hem de polikliniğimizin solunum ve alerji polikliniği olup, seçilmiş vakaların polikliniğimize yönlendirilmesinden kaynaklanmaktadır. Bu nedenle çocuklarda kronik öksürüğün etiyolojisine yönelik hem çok sayıda, hem de daha fazla olgu içeren çalışmalara ihtiyaç vardır.
