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Öğe The Effect of the SARS-CoV-2 Pandemic on Presentation with Diabetic Ketoacidosis in Children with New Onset Type 1 Diabetes Mellitus(Galenos Publishing House, 2023) Jalilova, A.; Ata, A.; Demir, G.; Işıklar, H.; Altınok, Y.A.; Özen, S.; Darcan, S.Objective: Diabetic ketoacidosis (DKA) is a life-threatening, acute complication of type 1 diabetes mellitus (T1DM). Infection is the most common precipitating factor for DKA, being responsible for more than 50% of such complications. The frequency and severity of DKA in children with T1DM, before and during the coronavirus disease 2019 outbreak were evaluated and compared with pre-pandemic presentation and severity rates. Methods: In total, 199 patients younger than 18 years were included in the study. Patients were divided into two groups: the Coronavirus disease-2019 (COVID-19) pandemic group (new onset T1DM presenting from March 2020 to March 2021; the control group included new onset T1DM from March 2016 to March 2020. Results: The rate of DKA at presentation was similar (p=0.393) during the pandemic period (58.3%) compared to the pre-pandemic years (44.8-64.3%). Although the percentage of DKA was similar, the rate of severe DKA in the COVID-19 group was higher than previous years. Although not significant, the duration of diabetes symptoms was longer in the COVID-19 period than the previous years. Conclusion: This study suggests that the rate of severe DKA, but not the overall rate of DKA, has increased during the COVID-19 pandemic compared to the prior four years. This may be due to the behavior of the parents of sick children and the limited access to the healthcare system. Despite this limited access, parental concern may have been sufficiently high to seek medical attention for their children, avoiding an increased frequency of DKA as the first presentation of new-onset T1DM. © 2023 by Turkish Society for Pediatric Endocrinology and Diabetes / The Journal of Clinical Research in Pediatric Endocrinology published by Galenos Publishing House.Öğe The impact of 21-gene recurrence score (RS) scores on treatment decisions: Retrospective evaluation in Turkish early-stage breast cancer (BC) patients(Amer Soc Clinical Oncology, 2011) Basaran, G.; Saglam, S.; Tansan, S.; Demirel, M.; Gokmen, E.; Aktan, S.; Goker, E.; Kaban, K. K.; Saip, P.; Demir, G.; Bavbek, S. E.; Mandel, N. M.; Tecimer, C.; Turhal, N. S.; Garipoglu, M.Öğe INSULIN INFUSION PUMP TREATMENT AT THE DIAGNOSIS : ANTHROPOMETRIC MEASUREMENTS, METABOLIC CONTROL AND ITS EFFECT ON INSULIN DOSES(Mary Ann Liebert, Inc, 2020) Er, E.; Ata, A.; Evin, F.; Isiklar, H.; Demir, G.; Ozen, S.; Goksen, D.[No abstract available]Öğe Multicentric Ipilimumab Experience in Turkish Patients with Metastatic Melanoma: MIPI-TURK at 3 years(Wiley-Blackwell, 2013) Sevinc, A.; Turna, H.; Ozdogan, M.; Buyukberber, S.; Demir, G.; Gokmen, E.; Mandel, N. M.; Paydas, S.; Akbulut, H.; Celik, I.Öğe Response of Some Tomato Cultivars and Wilt Species of Lycopersicon to Tomato Pith Necrosis(Int Soc Horticultural Science, 2009) Ustun, N.; Demir, G.; Saygili, H.; Saygili, H; Sahin, F; Aysan, YIn the study reactions of 31 tomato cultivars, 3 rootstock and some wild Lycopersicon (L. peruvianum var. humifusum, L. peruvianum f. glandulosum, L. hirsutum, L. pimpinellifolium, L. esculentum var. cerasiforme, L. chilense) species to tomato pith necrosis caused by Pseudomonas corrugata, Pseudomonas viridiflava, Pseudomonas cichori and Erwinia carotovora subsp. carotovora were determined. The plants grown in pots in greenhouse were artificially inoculated. Severity of the disease was assessed one month after inoculation. None of the cultivars tested were resistant to the strains except cultivars ACE 55 VF and Nun 2048 found resistant to E. carotovora subsp carotovora. In L. peruvianum f. glandulosum and L. peruvianum var humifusum resistance to the strains were determined. http://www.actahort.org/books/808/index.htmÖğe SENSOR AUGMENTED PUMP THERAPY EFFECTS GLYCEMIC VARIABILITY(Mary Ann Liebert, Inc, 2020) Evin, F.; Demir, G.; Cetin, H.; Ozen, S.; Darcan, S.; Goksen, D.[No abstract available]Öğe Six Months in Advanced Hybrid Closed Loop System in The Real World: Psychosocial Outcomes in Children And Adolescents With Type 1 Diabetes(Mary Ann Liebert, Inc, 2023) Jalilova, A.; Pilan, B. Şentürk; Demir, G.; Özbaran, B.; Köse, S. G.; Özen, S.; Darcan, S.[No abstract available]