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Öğe AGREEMENT OF PATIENT AND PHYSICIAN GLOBAL ASSESSMENT OF DISEASE ACTIVITY IN ADULT ONSET STILL'S DISEASE(Bmj Publishing Group, 2016) Kalyoncu, U.; Kasifoglu, T.; Kisacik, B.; Oksuz, M. F.; Omma, A.; Bes, C.; Cinar, M.; Pamuk, O. N.; Kucuksahin, O.; Akar, S.; Aksu, K.; Yildiz, F.; Onat, A. M.; Kanitez, N. A.; Erden, A.; Dalkilic, E.; Ermurat, S.; Hayran, M.Öğe The effects of an organic rearing system and dietary supplementation of an essential oil mixture on performance and meat yield of slow-growing broilers in two seasons(South African Journal Of Animal Sciences, 2014) Kucukyilmaz, K.; Bozkurt, M.; Cinar, M.; Catli, A. U.; Bintas, E.; Erkek, R.In this study, performance and carcass characteristics of slow-growing broiler chicks, reared in organic or conventional systems, and fed a diet with an essential oil mixture (EOM, 48 mg/kg diet), were evaluated in the autumn and spring seasons. The rearing system affected several performance indices, including body weight, feed intake and feed conversion ratio (FCR), but not mortality, within a high statistical significance at 42 and 81 days of age. However, this was observed only from 1 to 42 days in the spring trial. Dietary administration with EOM worsened the FCR at 42 and at 81 days of age in the autumn trial, but not in spring. Organically reared slow-growing chickens consumed less feed mixture per unit of body weight gain, but attained a higher final weight compared with those kept indoors. However, the effect was more pronounced in autumn, which displayed cooler temperatures and robust plant cover availability (i.e. lucerne and trifolium). The carcass yield and cut-up carcass yield were not affected by the rearing system, but EOM diet supplementation increased breast yield only in the spring. The results suggest that autumn conditions promote efficient organic chicken production in the subtropical climatic zone. The amount of herbage consumed represented up to 10% and 3% of the birds' daily protein and ether extract requirements, respectively. Supplementing the diet with a mixture of plant essential oils did not support the hypothesis that phytogenic compounds may favourably affect gut function and poultry performance.Öğe FACTORS ASSOCIATED WITH THE DEVELOPMENT OF ANTI-DRUG ANTIBODIESTOTUMOUR NECROSIS FACTOR INHIBITORS IN PATIENTS WITH AXIAL SPONDYLOARTHRITIS; A TWOYEAR FOLLOW-UP STUDY(Bmj Publishing Group, 2021) Ediboglu, E. Durak; Solmaz, D.; Kabadayi, G.; Ozmen, M.; Cinar, M.; Sargin, G.; Karadag, O.[No Abstract Available]Öğe IS THERE ANY ROLE OF IMMUNOGENICITY ON THE RESPONSE TO THE ANTI-TUMOR NECROSIS FACTOR ALPHA THERAPY IN PATIENTS WITH ANKYLOSING SPONDYLITIS: THE FIRST RESULTS OF A PROSPECTIVE COHORT STUDY(Bmj Publishing Group, 2017) Akar, S.; Cinar, M.; Sargin, G.; Karadag, O.; Kinikli, G.; Ozmen, M.; Gercik, O.; Kalyoncu, U.; Yilmaz, S.; Senturk, T.; Keser, G.; Hatemi, G.; Yargucu, F.; Ozguler, Y.; Cefle, A.; Kozaci, D.; Solmaz, D.; Kisacik, B.Öğe MALIGNANCY RISK IS INCREASED IN PATIENTS WITH SYSTEMIC SCLEROSIS(Bmj Publishing Group, 2013) Kasifoglu, T.; Bilge, N. S. Yasar; Yildiz, F.; Ozen, G.; Pehlivan, Y.; Yilmaz, N.; Tarhan, F.; Yilmaz, S.; Kucuk, A.; Emmungil, H.; Koca, S.; Cinar, M.; Korkmaz, C.; Direskeneli, H.; Arslantas, D.; Erken, E.; Can, G.; Ozmen, M.; Gonullu, E.; Kisacik, B.; Aksu, K.; Karadag, O.Öğe Risk factors for malignancy in systemic sclerosis patients(Springer London Ltd, 2016) Kasifoglu, T.; Bilge, S. Yasar; Yildiz, F.; Ozen, G.; Pehlivan, Y.; Yilmaz, N.; Tarhan, F.; Yilmaz, S.; Kucuk, A.; Emmungil, H.; Koca, S. S.; Cinar, M.; Direskeneli, H.; Erken, E.; Can, G.; Ozmen, M.; Gonullu, E.; Kisacik, B.; Aksu, K.; Karadag, O.; Kasifoglu, N.; Arslantas, D.; Sahin, F.; Keser, G.; Yavuz, S.; Birlik, M.; Onat, A. M.Systemic sclerosis (SSc) is an autoimmune connective tissue disease with multisystem involvement. An increased incidence of cancer in SSc patients compared with the general population has been reported in several reports. Our aims in this study were to determine the most common malignancies and to investigate the possible risk factors for the development of malignancy in patients with SSc. Three hundred forty SSc patients from 13 centers were included to the study. Data of the patients were obtained by evaluating their medical records retrospectively. A total of 340 patients with SSc were evaluated. Twenty-five of the patients had 19 different types of malignancy. Bladder cancer was the most common type of cancer with four patients and was followed by breast cancer with three patients, and cervix cancer and ovarian cancer with two patients each. Other types of cancers such as squamous cell skin cancer, adenocancer with an unknown origin, multiple myeloma, chronic myeloid leukemia, papillary thyroid cancer, larynx cancer, non-small cell lung cancer, follicular type non-Hodgkin lymphoma (NHL), endometrium cancer, colon cancer, uterus cancer, neuroendocrine tumor, glioblastoma multiforme, and soft tissue sarcoma were diagnosed in one patient each. The only cancer type that showed an association with cyclophosphamide dose was bladder carcinoma. Other malignancies did not show a correlation with age, sex, smoking, type and duration of the disease, autoantibodies, organ involvement, and dose and duration of cyclophosphamide therapy. Cancer may develop in any organ in patients with SSc. Continuous screening of the patients during a follow-up period is necessary for the early detection of the tumor development.Öğe Role of Rho-kinase in contractions of ureters from rabbits with unilateral ureteral obstruction(Elsevier Science Bv, 2008) Turna, B.; Cinar, M.; Canda, E.; Orhan, E.; Nalan, N.; Semerci, B.; Nazli, O.; Buyukafsar, K.
