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Öğe Effects of intra-articular hyaluronic acid and corticosteroid therapies on articular cartilage in experimental severe osteoarthritis [3](2006) Eyigor S.; Hepguler S.; Sezak M.; Öztop F.; Capaci K.[No abstract available]Öğe Joint hypermobility syndrome and mitral valve prolapse in panic disorder(2004) Gulpek D.; Bayraktar E.; Pirildar Akbay S.; Capaci K.; Kayikcioglu M.; Aliyev E.; Soydas C.Objective: The purpose of this study is to test the association between joint hypermobility syndrome (JHS) and panic disorder (PD) and to determine whether mitral valve prolapse (MVP) modifies or accounts in part for the association. Method: A total of 115 subjects are included in this study in three groups. Group I (n=42): panic disorder patients with MVP. Group II (n=35): panic disorder patients without mitral valve prolapse. Group III (n=38): control subjects who had mitral valve prolapse without any psychiatric illness. Beighton criteria were used to assess joint hypermobility syndrome. Two-dimensional and M-mode echocardiography was performed on each subject to detect mitral valve prolapse. Results: Joint hypermobility syndrome was found in 59.5% of panic disorder patients with mitral valve prolapse, in 42.9% of patients without mitral valve prolapse and in 52.6% of control subjects. Beighton scores was 4.93±2.97 in group I, 4.09±2.33 in group II, and 4.08±2.34 in group III. There was no significant difference between groups according to Beighton scores. Conclusion: We did not detect a statistically significant relationship between panic disorder and joint hypermobility syndrome. Mitral valve prolapse and joint hypermobility syndrome are known to be etiologically related and we suggest that mitral valve prolapse affects the prevalence of joint hypermobility syndrome in the panic disorder patients. © 2004 Published by Elsevier Inc.Öğe Radioisotope synovectomy with rhenium186 in haemophilic synovitis for elbows, ankles and shoulders(2008) Kavakli K.; Aydogdu S.; Taner M.; Duman Y.; Balkan C.; Karapinar D.Y.; Saydam, G..; Capaci K.; Oktay A.We have performed 221 radioisotope synovectomy (RS) in more than 150 children and young adults with haemophilia, age ranging 3-30years (mean 15) in Ege Hemophilia Center, Izmir, Turkey for last 7years. We always preferred to use Yttrium 90 (Y90) for knees; however, since 2005, we started using rhenium 186 (Re186) for medium-sized joints with respect to safety. In this article, we have evaluated long-term experience ranging from 6months to 3years (mean 18months) with Re186 for elbows (n = 35), ankles (n = 26) and shoulders (n = 2) in total of 63 RS procedures for 49 patients. Their age range was 3-30 years and mean age was 15.5. Two mCi of Re186 intra-articularly injected for treating target joints and chronical synovitis. After RS, joint bleedings were decreased for all patients. The best results were obtained for all joints in patients with grade-II synovitis as like earlier experience with Y90. Excellent rates (no bleeding) were observed in grade-II synovitis in 81% and 46% for elbows vs. 86% and 57% for ankles after 6months and after 1 year follow-up of patients, respectively. In grade-III synovitis, excellent rates were 53% and 25% for elbows and 44% and 29% for ankles, respectively. In five joints for five patients, repeated injections were needed for better outcome. No adverse events such as radioisotope leakage, local inflamatory reactions or malignancy development were observed during and after RS. For medium-sized joints, RS with Re186 seems to be either effective or safe treatment method. Our results confirm those previously published by others on the value of Re186 synoviorthesis in medium-sized joints in haemophilia patients. After this experience, we changed our protocol and we use Re 186 for all medium-sized joints for treating chronical synovitis. © 2008 Blackwell Publishing Ltd.