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Öğe Endobronchial metastasis from osteosarcoma of bone - Treatment with intraluminal radiotherapy(Amer Coll Chest Physicians, 1999) Mogulkoc, N; Goker, E; Atasever, A; Veral, A; Ozkok, S; Bishop, PWLung parenchymal metastases are common manifestations in patients with osteosarcoma; however, spread to the major airway itself is extremely rare. We present a young man who had been previously treated with surgical resection following preoperative chemotherapy and immediate postsurgical adjuvant chemotherapy for proximal tibial osteosarcoma. He developed metastasis to the major airways. The patient was treated with intraluminal radiotherapy (ILT) for the endobronchial metastasis. This is the first report of an endobronchial osteosarcoma that was treated with ILT with a complete endoscopic response. ILT provided excellent palliation in this particular case.Öğe Intracardiac thrombus in Behcet's disease - A systematic review(Amer Coll Chest Physicians, 2000) Mogulkoc, N; Burgess, MI; Bishop, PWBackground: Intracardiac thrombus formation is a rare but serious complication of Behcet's disease. We aimed to review the clinical and pathologic correlates of cardiac thrombus formation in the context of Behcet's disease. Methods and results: A comprehensive search of the medical literature was conducted using MEDLINE including bibliographies of all selected articles. Although the disease has a unique geographic distribution, being most common in the population of the ancient Silk Route, cases complicated by intracardiac thrombus have mostly originated from the Mediterranean basin and the Middle East. Young men appear to be most at risk, with the right heart the most frequent site of involvement. The first symptoms and signs of the disease frequently precede systemic organ manifestations. In those cases in which intracardiac thrombus occurs, it is apparent in more than half of cases on first recognition of the disease, Conclusion: A diagnosis of Behcet's disease should be considered if a patient presents with a mass in the right-sided cardiac chambers, even in the absence of the characteristic clinical features of the condition. This is particularly applicable if the patient is a young man from the Mediterranean basin or the Middle East.Öğe Pulmonary Langerhans' cell histiocytosis - Radiologic resolution following smoking cessation(Amer Coll Chest Physicians, 1999) Mogulkoc, N; Veral, A; Bishop, PW; Bayindir, U; Pickering, CAC; Egan, JJWe describe two patients with histologically pr-oven pulmonary Langerhans' cell histiocytosis in whom radiologic improvement occurred following smoking cessation. The patients had 23- and 25-pack-year smoking histories, respectively. High-resolution CT revealed multiple small nodules, located predominantly in the upper and middle lung fields. There was a close temporal relationship between smoking cessation and radiologic improvement.Öğe An unusual presentation of anti-Jo-1 syndrome, mimicking lung metastases, with massive pleural and pericardial effusions(Lippincott Williams & Wilkins, 2006) Mogulkoc, N; Kabasakal, Y; Ekren, PK; Bishop, PWWe report a case of anti-Jo-1 syndrome (a rare autoimmune condition that may manifest with various forms of interstitial lung disease), which in our case presented Unusually with multiple pulmonary nodules, mimicking carcinoma. She Subsequently developed pleural and pericardial effusions (which are rare in this syndrome), myopathy, and "mechanic's hand," with similar lesions on the feet. "Mechanic's foot" noted in this patient has not been previously described. She initially responded well to immunosuppression but has subsequently progressed to pulmonary fibrosis.