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Öğe A comparison of maximal oxygen uptake obtained from different tests in chronic obstructive pulmonary disease patients(Baycinar Medical Publ-Baycinar Tibbi Yayincilik, 2014) Ekren, Pervin Korkmaz; Gurgun, Alev; Karapolat, Hale; Ozdemir, Pelin; Toreyin, Nur; Tasbakan, Sezai; Basoglu, Ozen Kacmaz; Bacakoglu, FezaBackground: This study aims to assess the correlation between maximal oxygen uptake (peakVO(2)) during cardiopulmonary exercise test (CPET) and peakVO(2) obtained from incremental shuttle walking test (ISWT) in patients with chronic obstructive pulmonary disease (COPD) and to investigate their relationship with quality of life. Methods: Data of 38 stable COPD patients (35 males, 3 females; mean age 64.6 +/- 8.3 years; range 48 to 82 years) who completed outpatient pulmonary rehabilitation (PR) program and assessed by CPET and ISWT through treadmill test was retrospectively analyzed. Pulmonary rehabilitation was performed during eight weeks. PeakVO(2) measured via breath-by-breath technique during CPET. PeakVO(2) from ISWT distance was calculated by the formula "4.19+ [0.025x ISWT distance]". Borg scale was used for the evaluation of dyspnea severity before and after PR, whereas St. George's Respiratory Questionnaire was used for quality of life. Results: PeakVO(2) on CPET were found 15.9 +/- 5.1 ml/min/kg before PR and 17.3 +/- 5.3 ml/min/kg after PR (p=0.001). The peakVO(2) calculated with ISWT was 11.6 +/- 3.2 ml/min/kg before PR and 13.4 +/- 3.2 ml/min/kg after PR (p<0.001). Incremental shuttle walking test distance increased from 296.1 +/- 128.9 meters to 367.1 +/- 129.1 meters (p<0.001). A significant relationship between peakVO(2) on CPET and calculated peakVO(2) from ISWT before and after PR (p=0.001, p=0.005, respectively). A moderate positive correlation (r=0.50) and a weak correlation (r=0.449) were found before and after PR, respectively. Dyspnea was reduced and quality of life and walking distance were improved after PR. There were significant but weak correlations between activity, impact, total score of St. George's Respiratory Questionnaire and peakVO(2) on CPET before and after PR (p<0.05). Conclusion: Incremental shuttle walking test can also be used for the evaluation of exercise capacity in COPD patients. Although it is an inexpensive and easy-to-use method, CPET should be preferred to achieve objective results.Öğe Effect of Short Term Use of PAP Treatment on Metabolic Parameters in Patients with Obstructive Sleep Apnea(European Respiratory Soc Journals Ltd, 2020) Atik, Nazli Deniz; Tasbakan, Sezai; Basoglu, Ozen Kacmaz[No Abstract Available]Öğe Exudative pleural effusion due to brucellosis in a patient with chronic obstructive pulmonary disease(Royal Soc Medicine Press Ltd, 2006) Zengi, Ayhan; Elmas, Funda; Tasbakan, Meltem; Basoglu, Ozen Kacmaz; Ozhan, Mustafa HikmetPleural involvement is a rare presentation of brucellosis. We report a patient referred for the evaluation of fever, right-sided pleural effusion and hilar lymph node enlargement. The pleural fluid revealed exudative characteristics with the predominance of neutrophils. Brucella melitensis was isolated from bone marrow, pleural effusion and blood cultures. The diagnosis was also confirmed by demonstration of a high Brucella agglutinin titre. The patient was successfully treated with rifampicin and doxicycline for three months.Öğe The factors affecting noninvasive mechanical ventilation failure in COPD exacerbations(Tubitak Scientific & Technical Research Council Turkey, 2012) Bacakoglu, Feza; Tasbakan, Mehmet Sezai; Basoglu, Ozen Kacmaz; Oz, Adnan Tolga; Urkmez, Sedat; Midilli, Meltem; Ekren, Pervin Korkmaz; Gurgun, AlevAim: To evaluate causes of noninvasive mechanical ventilation (NIMV) failure. The rate of NIMV failure in respiratory failure due to chronic obstructive pulmonary disease (COPD) exacerbations was reported as 5%-40%. Materials and methods: The necessity of endotracheal intubation was accepted as NIMV failure. The causes of NIMV failure were assessed in 54 patients (45 males; mean age: 67.7 +/- 11.0 years) treated with NIMV because of COPD exacerbations and respiratory failure in an intensive care unit (ICU). Results: There was NIMV failure in 20 patients (37.0%). The rates of hospital-acquired pneumonia and in-hospital mortality were higher (P = 0.003 and P = 0.002, respectively) and the duration of ICU stay was longer (P < 0.0001) in patients with NIMV failure. On admission, arterial pH, serum albumin, and Glasgow Coma Scale levels were lower (P = 0.032, P = 0.024, and P = 0.013, respectively) in the NIMV failure group. Arterial pH was lower (P = 0.039) and respiratory rate was higher (P = 0.010) after 1 h, and the PaO2/FiO2 rate was lower (P = 0.017) and respiratory and heart rates were higher (P = 0.002 and P = 0.020, respectively) after 3 h in the NIMV failure group. Conclusion: The present data strongly suggest that baseline and follow-up clinical and arterial blood gas evaluations can give important clues about NIMV failure in COPD exacerbations.Öğe The influence of the lateral pharyngeal wall anatomy on snoring and sleep apnoea(Pakistan Medical Assoc, 2015) Korhan, Ibrahim; Gode, Sercan; Midilli, Rasit; Basoglu, Ozen KacmazObjectives: To elucidate the variations of the lateral pharyngeal wall anatomy on physical examination and to assess the clinical importance of the examination of the lateral pharyngeal wall on the presence and severity of obstructive sleep apnoea syndrome. Methods: The cross-sectional study was conducted at Ege University Medical School, Izmir, Turkey, between May 2010 and April 2011. The patients were divided into four equal groups: Group 1 - snoring without apnoea (age 20-40); Group 2 - snoring without apnoea (age 40-60); Group 3 - apnoea-hypopnoea index <5/hr; Group 4: apnoea-hypopnoea index >30/hr. Calibrated oropharynx pictures were taken. Distance between palatoglossal and palatopharyngeal arches, height of palatoglossal and palatopharyngeal arches, uvula width, uvula length and distance between tonsils were measured. SPSS 17 was used for statistical analysis. Results: Of the 80 patients in the study, 44(55%) were men. Mean distance between palatopharyngeal and palatoglossal arches were 1.55+/-0.34cm and 2.70+/-0.43cm respectively. Mean height of palatopharyngeal and palatoglossal arches were 0.60+/-0.21cm and 1.37+/-0.36cm respectively (p>0.05). Mean uvula width and uvula length were 0.80+/-0.12cm and 1.25+/-0.27cm respectively (p>0.05). Mean distance between tonsils was 2.24+/-0.56cm (p>0.05). Distance between palatopharyngeal arches was significantly different between groups 3 and 4 (p<0.05). Conclusions: Palatopharyngeal arch anatomy was found to be significantly associated with obstructive sleep apnoea syndrome severity, especially in patients with normal or small tonsil size. Patients with the palatopharyngeal arches, which narrow the oropharyngeal inlet more than the tonsils, should further be investigated with polysomnography.
