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Öğe Antimicrobial activities of methanol extracts and essential oils of Rosmarinus officinalis, depending on location and seasonal variations(Elsevier Sci Ltd, 2007) Yesil-Celiktas, O.; Kocabas, E. E. Hames; Bedir, E.; Sukan, F. Vardar; Ozek, T.; Baser, K. H. C.Rosmarinus officinalis is widely found in the lands of Aegean and Mediterranean regions of Turkey. The goal of this work was to test the antimicrobial activity of the essential oils and methanolic extracts of R. officinalis collected from three different regions at four different time intervals of the year against Staphylococcus aureus, Proteus vulgaris, Pseudomonas aeruginosa, Klebsiella pneumonia, Enterococcus feacalis, Escherichia coli, Staphylococcus epidermidis, Bacillus subtilis and Candida albicans. Essential oils were obtained from the aerial parts of the plant by using a Clevenger apparatus, for 4 h. After distillation, the distillates were filtered, air-dried and then extracted by using a Soxhlet apparatus for 9 h to obtain the methanolic extracts. The antimicrobial activities of the methanolic extracts were tested by the disc diffusion technique. The antimicrobial activities of the essential oils obtained from R. officinalis were determined by minimum inhibitory concentration (MIC). The results indicated that the tested bacteria were sensitive to the essential oils and partially to the methanolic extracts. The antimicrobial activities of the essential oils against the tested bacteria differed, depending on location and seasonal variations. (c) 2005 Elsevier Ltd. All rights reserved.Öğe Chemical composition and antimicrobial activity of the essential oil of Anthemis wiedemanniana from Turkey(Springer, 2007) Kivcak, B.; Mert, T.; Saglam, H.; Ozturk, T.; Kurkcuoglu, M.; Baser, K. H. C.The chemical composition and antimicrobial activity of the essential oil from aerial parts of Anthemis wiedemanniana, an endemic taxon of Turkey, were investigated. Linalool (12.75%), 1,8-cineole (8.49%), hexadecanoic acid (6.09%), and chrysanthenone (5.67%) were found to be the main components among the 122 compounds characterized in the essential oil of Anthemis wiedemanniana. Antimicrobial activities were reported against 12 microorganisms and five yeast-like fungi by the disc diffusion method.Öğe CHEMICAL COMPOSITION AND ANTIMICROBIAL ACTIVITY OF THE ESSENTIAL OILS OF THREE Anthemis SPECIES FROM TURKEY(Springer, 2009) Kurtulmus, A.; Fafal, T.; Mert, T.; Saglam, H.; Kivcak, B.; Ozturk, T.; Demirci, B.; Baser, K. H. C.Öğe CHEMICAL COMPOSITION AND ANTIMICROBIAL ACTIVITY OF THE ESSENTIAL OILS OF THREE Anthemis SPECIES FROM TURKEY(Springer, 2009) Kurtulmus, A.; Fafal, T.; Mert, T.; Saglam, H.; Kivcak, B.; Ozturk, T.; Demirci, B.; Baser, K. H. C.Öğe Composition of the essential oils of Centaurea aphrodisea, C. polyclada, C. athoa, C. hyalolepis and C. iberica(Georg Thieme Verlag Kg, 2011) Erel, Baykan S.; Demirci, B.; Demir, S.; Karaalp, C.; Baser, K. H. C.Öğe Determination of Fatty Acid and Essential Oil Constituents and Biological Activities on Ranunculus pedatus Subsp pedatus(Asian Journal Of Chemistry, 2014) Erdogan, T.; Gonenc, T.; Demirci, B.; Kivcak, B.; Baser, K. H. C.In this study, the fatty-acid profile, essential-oil composition and cytotoxic and antioxidant activities of the aerial parts of Ranunculus pedatus Waldst. & Kit. subsp. pedatus have been examined. Linoleic acid (24.47 %) and palmitoleic acid (18.94 %): were identified as major components by GC-FID and GC/MS analysis. Unsaturated fatty acids were found in higher amounts than saturated fatty acids. The essential-oil composition was also analyzed by GC and GC/MS and 29 components were characterized. Protoanemonin (14.3 %), phytol (13.7 %); alpha-bisabolol (7.9 %), (Z)-3-hexenol (7.8 %) and octanol (6.7 %) were determined as the main constituents of the essential oil. Ethanol and chloroform extracts were investigated for the cytotoxic activity against PC3, HeLa and Vero human cancer cell lines and both : of the extracts were found to be effective On HeLa. The IC50 values were determined as 47 and 78.4 mg/mL, for methanol and chloroform : extracts respectively. Antioxidant activity of chloroform and ethanol extracts were evaluated by DPPH assay. The total phenolics and flavonoid contents of the extracts were determined by Folin-Ciocalteau and aluminium chloride methods, respectively. The ethanol , extract was found to possess 67.54 % DPPH inhibition. The results obtained in the antioxidant activity assay were in positive correlation le with the total phenolics and flavonoid contents of the extracts.Öğe Effect of dietary essential oil mixture on performance of laying hens in summer season(South African Journal Of Animal Sciences, 2006) Cabukt, M.; Bozkurt, M.; Alcicek, A.; Catli, A. U.; Baser, K. H. C.The experiment was conducted to evaluate the effects of dietary supplements of either an essential oil mixture (EOM) or a mannan oligosaccharide (MOS) as alternatives to an antibiotic feed additive (avilamycin) for layers kept under hot summer conditions. Four hundred and eighty 54-week old Nick-Brown hens were assigned to four dietary treatments. Each treatment consisted of four replications of 10 cages (three hens per cage). The treatment groups were: 1) Control: Basal diet without additive; 2) Basal diet plus antibiotic (10 mg avilamycin/kg feed); 3) Basal diet plus 1 g MOS/kg feed; 4) Basal diet plus 24 mg EOM/kg feed. Performance of laying hens was affected by dietary treatments. Dietary supplementation of EOM and MOS significantly increased egg production compared with control and antibiotic groups. There were no significant differences in feed consumption between treatments. The EOM significantly improved feed conversion ratio above that of the control group. Egg weights were significantly different between treatments. Laying hens consuming MOS produced significantly lower egg weights than the other groups, while egg weights in the EOM, antibiotic and control groups did not differ significantly. Cracked-broken egg rate was decreased by dietary addition of EOM, MOS and antibiotic compared with the control. Number of deaths among hens was significantly affected by dietary treatments with the number of deaths in the MOS treatment being significantly lower than in the other treatments. The performance of laying hens during the summer season could be maintained with inclusions of EOM and MOS in the diet.Öğe The essential oil composition of aerial parts of Anthemis tricolor Boiss. from Cyprus(Taylor & Francis Ltd, 2014) Karaalp, C.; Erel, S. Baykan; Nalbantsoy, A.; Guecel, S.; Demirci, B.; Baser, K. H. C.The water-distilled essential oil from the aerial parts of Anthemis tricolor Boiss. (Asteraceae), an endemic taxon from Cyprus, was analysed by GC and GC-MS. The analysis revealed 40 compounds accounting for 84.5% of the oil. Muurola-4,11-diene (20.2%), beta-caryophyllene (9.1%) and germacrene-D (5.5%) were the main compounds of A. tricolor. To the best of our knowledge, this is the first detailed study of the essential oil composition of A. tricolor collected from Cyprus.
