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Öğe Design Of A Radiolabeled Polymeric Drug Carrier System (99)mTc(CO)(3)-Oxaliplatin-PEG-PLA(Springer, 2017) Senocak, K.; Teksoz, S.; Kilcar, A. Yurt; Ucar, E.; Aydin, B.Öğe The effect of spreader size on fracture resistance of maxillary incisor roots(Blackwell Publishing, 2008) Piskin, B.; Aydin, B.; Sarikanat, M.Aim To assess the effect of spreader size used during cold lateral compaction of gutta-percha on fracture resistance of roots in maxillary incisor teeth. Methodology The crowns of 50 human maxillary incisor teeth having no carious lesions, no fracture or crazing were resected 2 mm coronal to the cemento-enamel junction. The root canals of the teeth were prepared as follows: Group 1: No canal preparation. Group 2: Preparation using the stepback technique to a size 40 master apical file. Group 3: Canal preparation to size 40 and filling with laterally compacted gutta-percha; the first spreader used was equal to size 40. Group 4: Same as group 3 except the first spreader was equal to size 35. Group 5: Same as group 3 except the first spreader was equal to size 25. For each root, a simulated periodontal ligament was prepared. The roots were than mounted in polyester resin and fractured vertically on a universal testing machine (Shimadzu, Tokyo, Japan). The fracture values of teeth were analysed using Kruskal-Wallis and Mann-Whitney U-tests (P = 0.05). Results The uninstrumented group had the highest fracture resistance; instrumented, but unfilled roots, demonstrated the lowest resistance values (P = 0.009). There were no differences between the uninstrumented group and group 5 in which a size 25 spreader was used during filling. Use of spreaders larger than size 25 caused a significant reduction in fracture resistance of roots (P < 0.05). Conclusions Spreader size used during lateral compaction of gutta-percha can affect the fracture resistance of roots in extracted teeth.Öğe The effect of TAB duration and pelvic RT in prostate cancers with gleason score 8-10: TROG study(Elsevier Ireland Ltd, 2017) Ozyigit, G.; Onal, C.; Igdem, S.; Alicikus, Z. Arican; Iribas, A.; Akin, M.; Yalman, D.; Cetin, I.; Aksu, M. G.; Atalar, B.; Dincbas, F.; Aydin, B.; Sert, F.; Yildirim, C.; Gorken, I. B.; Agaoglu, F. Y.; Korcum, A. F.; Ozkok, S.; Darendeliler, E.; Akyol, F.Öğe Effectiveness of HERO 642 versus Hedstrom files for removing gutta-percha fillings in curved root canals: an ex vivo study(Wiley-Blackwell Publishing, Inc, 2009) Aydin, B.; Kose, T.; Caliskan, M. K.P>Aim To compare the effectiveness of gutta-percha removal and the maintenance of canal anatomy when using the HERO 642 system or Hedstrom files (H-files) in mandibular molar teeth. Methodology The root canals of 40 mandibular molar teeth were instrumented using H-files and filled with gutta-percha and sealer. After 1 year in storage, the roots were sectioned horizontally to provide apical, middle and coronal root thirds. Sections were photographed, and an individual muffle was produced for each tooth. Teeth were randomly divided into four groups (n = 10) and the gutta-percha removed using either the HERO 642 system or H-files, with or without solvent. Digital images of the root canals were then re-taken. Root thirds were inspected for lateral perforations, and the percentage of the residual canal filling was determined on postoperative images. Transportation and centring ratio were calculated using preoperative and postoperative images of the cross-sections of root thirds. Results H-files groups were associated with less filling material than the HERO 642 system (H-files-HERO 642 P = 0.056, H-files-HERO 642+solvent P = 0.041, H-files + solvent-HERO 642 P = 0.018, H-files + solvent-HERO 642 + solvent P = 0.016). The percentage of residual filling material was similar in the apical thirds, and the contribution of solvent to canal debridement was not statistically significant (P > 0.05). Perforation occurred mesiobuccally in 48% of specimens in the apical sections of mesial roots. There were no significant differences for centring ratio, transportation and perforation rate between groups. Conclusions H-files left less gutta-percha overall; however, there was no difference in the apical third. The effect of solvent was not remarkable. Both instrument systems created a large number of perforations.Öğe Effectiveness of HERO 642 versus Hedstrom files for removing gutta-percha fillings in curved root canals: an ex vivo study(Wiley-Blackwell Publishing, Inc, 2009) Aydin, B.; Kose, T.; Caliskan, M. K.P>Aim To compare the effectiveness of gutta-percha removal and the maintenance of canal anatomy when using the HERO 642 system or Hedstrom files (H-files) in mandibular molar teeth. Methodology The root canals of 40 mandibular molar teeth were instrumented using H-files and filled with gutta-percha and sealer. After 1 year in storage, the roots were sectioned horizontally to provide apical, middle and coronal root thirds. Sections were photographed, and an individual muffle was produced for each tooth. Teeth were randomly divided into four groups (n = 10) and the gutta-percha removed using either the HERO 642 system or H-files, with or without solvent. Digital images of the root canals were then re-taken. Root thirds were inspected for lateral perforations, and the percentage of the residual canal filling was determined on postoperative images. Transportation and centring ratio were calculated using preoperative and postoperative images of the cross-sections of root thirds. Results H-files groups were associated with less filling material than the HERO 642 system (H-files-HERO 642 P = 0.056, H-files-HERO 642+solvent P = 0.041, H-files + solvent-HERO 642 P = 0.018, H-files + solvent-HERO 642 + solvent P = 0.016). The percentage of residual filling material was similar in the apical thirds, and the contribution of solvent to canal debridement was not statistically significant (P > 0.05). Perforation occurred mesiobuccally in 48% of specimens in the apical sections of mesial roots. There were no significant differences for centring ratio, transportation and perforation rate between groups. Conclusions H-files left less gutta-percha overall; however, there was no difference in the apical third. The effect of solvent was not remarkable. Both instrument systems created a large number of perforations.Öğe Expression of cyclin D1 and its relation with ER, PgR, C-erbB2, Ki-67, and p53 in breast cancer.(Amer Soc Clinical Oncology, 2010) Haydaroglu, A.; Demirci, S.; Demir, D.; Aydin, B.; Bolukbasi, Y.; Zekioglu, O.; Yeniay, L.; Ozdemir, N.; Gokmen, E.; Ylmaz, R.Öğe Preservice science teachers’ informal reasoning about hydroelectric power issue: The effect of attitudes towards socio-scientific issues and media literacy(Ismail Sahin, 2020) Namdar, B.; Aydin, B.; Raven, S.The purpose of this paper is to examine the role of media literacy and attitudes towards socioscientific issues as two major predictors of informal reasoning. A sample of 208 preservice science teachers completed an open-ended informal reasoning questionnaire on hydroelectric power plant issue, media literacy level determination scale, and attitudes towards socio-scientific issues scale. In this study, descriptive research method was used. We used both qualitative and quantitative methods to analyze the data. Results indicated that the participants frequently used ecological-oriented arguments. The participants least used health-oriented arguments. Regarding reasoning qualities, the participants typically created supportive arguments, rather than counterarguments and rebuttals. Confirmatory factor analysis revealed validity and reliability evidence consistent with previous research. Multiple regression analyses revealed that perceived level of media literacy predicted informal reasoning. However, attitudes towards socioscientific issues did not explain informal reasoning. We offer implications for science teacher education programs. © 2020, Ismail Sahin. All rights reserved.Öğe Structural Changes in the Intestinal Mucosa of the Wistar-albino Rats after Irradiation and the Protective Effect of Ascorbic Acid(Elsevier Science Inc, 2011) Yalman, D.; Aydin, B.; Doganavsargil, B.; Kamer, S.; Demirci, S.; Aras, A.