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Optimization of prednisolone acetate-loaded chitosan microspheres using a 2(3) factorial design for preventing restenosis
(Informa Healthcare, 2010) Sarisozen, Can; Arica, Betuel; Orman, Mehmet N.; Hincal, A. Atilla; Calis, Sema
Prednisolone acetate (PA)-loaded microspheres were prepared by the spray-drying technique using different polymer (1% and 2%) and drug concentrations (10% and 20%). To obtain the optimum formulation, a three-factor two-level (2