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Öğe Apical hypertrophic cardiomyopathy can mimic ischemic, heart diseases(Elsevier Science Bv, 2007) Duygu, H.; Zoghi, M.; Nalbantgil, S.; Ozerkan, F.; Akilli, A.; Akin, M.Öğe A circadian rhythm of syncope in patients with vasovagal syncope(Oxford Univ Press, 2006) Zoghi, M.; Duygu, H.; Nalbantgil, S.; Yavuzgil, O.; Akin, M.; Payzin, S.; Akilli, A.Öğe Effect of Aortic Valve Opening Pattern on Endothelial Function After Continuous-Flow Left Ventricular Assist Device Implantation(Lippincott Williams and Wilkins, 2023) Kaya, E.; Kocabaş, U.; Şimşek, E.; Nalbantgil, S.; Engin, Ç.; Özbaran, M.; Akilli, A.This study aimed to evaluate the effects of aortic valve opening patterns on endothelial functions in patients undergoing continuous-flow left ventricular assist device (CF-LVAD) implantation. This study included 43 patients who underwent CF-LVAD implantation and 35 patients with heart failure reduced ejection fraction (HFrEF; control group). The CF-LVAD group was divided into three subgroups based on aortic valve opening patterns: open with each beat, intermittently opening, and not opening groups. Flow-mediated dilatation (FMD) and pulsatility index (PI) were compared before and 3 months after CF-LVAD implantation. Cardiopulmonary exercise test (CPET) and 6 minute walk test (6-MWT) scores were measured at baseline and follow-up in the CF-LVAD group. The mean FMD and PI of patients in the CF-LVAD group reduced 3 months after implantation. Patients with intermittently opening and not opening aortic valves had worse endothelial function at follow-up. Before and 3 months after implantation FMD% did not significantly differ in patients whose aortic valves were open with each beat (4.72 ± 1.06% vs. 4.67 ± 1.16%, p = 0.135). Pulsatility index changes paralleled FMD changes. Cardiopulmonary exercise test and 6-MWT scores improved after implantation but without significant differences between subgroups. Maintaining normal aortic valve function after CF-LVAD implantation may reduce endothelial dysfunction; however, larger studies are needed for long-term clinical effects. © 2023 Lippincott Williams and Wilkins. All rights reserved.Öğe Effect of aortic valve opening pattern on endothelial functions after continuous flow left ventricular assist device implantation(Wiley, 2017) Kaya, E.; Simsek, E.; Nalbantgil, S.; Akilli, A.; Ozturk, P.; Engin, C.; Yagdi, T.; Ozbaran, M.Öğe Effect of levosimendan on left atrial functions in patients with ischemic heart failure(Oxford Univ Press, 2007) Duygu, H.; Ozerkan, F.; Zoghi, M.; Nalbantgil, S.; Akilli, A.; Akin, M.Öğe The effect of levosimendan on left ventricular systolic and diastolic function and systolic pulmonary artery pressure in patients taking carvedilol(Elsevier Science Bv, 2007) Duygu, H.; Zoghi, M.; Nalbantgil, S.; Ozerkan, F.; Erturk, U.; Onder, R.; Akilli, A.; Akin, M.Öğe Effect of levosimendan on right ventricular systolic and diastolic functions in patients with ischaemic heart failure(Wiley, 2008) Duygu, H.; Ozerkan, F.; Zoghi, M.; Nalbantgil, S.; Yildiz, A.; Akilli, A.; Akin, M.; Nazli, C.; Ergene, O.Objectives: Levosimendan is a novel positive inotropic calcium sensitiser agent used in acute left heart failure. In this study, the effect of levosimendan on the right ventricular systolic and diastolic functions was evaluated by tissue Doppler comparing them with dobutamine in patients with ischaemic heart failure. Methods: Patients having an acute decompensated heart failure with ischaemic cardiomyopathy and left ventricular ejection fraction < 40% were included in the study. Before and 24-h after treatment, peak systolic (Sa), peak early (Ea), peak late (Aa) diastolic annular velocities and Ea/Aa ratio from tricuspid lateral annulus by tissue Doppler and systolic pulmonary artery pressure (SPAP) were measured. Results: Sa, Ea and the Ea/Aa ratio were significantly increased in the levosimendan group whereas SPAP was significantly reduced. In the dobutamine group, no significant differences were observed in the Sa, Ea, Aa and Ea/Aa ratio in spite of a significant reduction in SPAP. Decrease in SPAP was greater in the levosimendan group (p = 0.002). Conclusion: Levosimendan improves right ventricular systolic and diastolic functions.Öğe Endothelial functions in myocardial bridge: Comparison and correlation between FMD and inflammation(Oxford Univ Press, 2006) Duygu, H.; Zoghi, M.; Nalbantgil, S.; Ozerkan, F.; Akilli, A.; Akin, M.Öğe The role of tilt training in preventing recurrent syncope patients with vasovagal syncope(Blackwell Publishing, 2007) Zoghi, M.; Duygu, H.; Turk, U.; Akyuz, S.; Oezerkan, F.; Akilli, A.; Akin, M.
