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Öğe Acute myocardial infarction in a young man caused by centipede sting(B M J Publishing Group, 2006) Yildiz, A; Biceroglu, S; Yakut, N; Bilir, C; Akdemir, R; Akilli, AIt is known that insects can cause various clinical effects such as myocardial ischaemia and hypotension from vasospasm and the myocardial toxic effects of the venom and anaphylaxis. Although myocardial ischaemia resulting from centipede sting has been reported once before, myocardial injury has not. In this report, the authors present the case of a 20 year old male patient bitten by a centipede and admitted to the emergency room with chest pain, abnormal electrocardiographic findings, and increased cardiac enzymes ( cardiac troponin T) suggesting acute myocardial infarction.Öğe The angiographic correlation between ST segment depression in noninfarcted leads and the extent of coronary artery disease in patients with acute inferior myocardial infarction: A clue for multivessel disease(Elsevier Science Inc, 2003) Zoghi, M; Gurgun, C; Yavuzgil, O; Turkoglu, I; Kultursay, H; Akilli, A; Akin, M; Turkoglu, CBACKGROUND: Although reciprocal ST segment depression (RSTD) in patients with acute inferior myocardial infarction is a common electrocardiogram finding, its significance is not yet established. In this prospective study, the relationship between RSTD and the extent of coronary artery disease (CAD) was investigated. PATIENTS AND METHODS: One hundred eighty-eight patients with acute inferior myocardial infarction who received thrombolytic therapy were enrolled in this study. The magnitude and location of ST segment depression in noninfarcted leads and the maximum ST segment elevation (STEmax) in inferior leads were measured. All patients were divided into two main groups according to the presence of RSTD and five subgroups according to the location of RSTD, the maximum RSTD and the STEmax. The coronary angiography was performed in all patients 28 4 days after acute myocardial infarction. RESULTS: There were no significant differences in the proportion of coronary disease risk factors in patients with, versus those without, RSTD (P=0.6). Multivessel CAD was present in 63 of the 108 (58%) patients with RSTD and in 32 of the 80 (40%) patients with no RSTD (P=0.02). According to the location of reciprocal changes, multivessel disease was present in significantly more patients with anterior RSTD concomitant with or without lateral ST segment depression (P=0.01 and P=0.03, respectively); the proportion of single vessel disease was greater in patients with only lateral RSTD (P=0.02). In addition, the presence of anterior RSTD to a greater magnitude than the STEmax in inferior myocardial infarction increases the likelihood of multivessel disease (P=0.006). CONCLUSIONS: The presence of RSTD during an acute inferior myocardial infarction correlates with the presence of multivessel CAD and may not be only an electrical phenomenon.Öğe The angiographic correlation between ST segment depression in noninfarcted leads and the extent of coronary artery disease in patients with acute inferior myocardial infarction: A clue for multivessel disease(Elsevier Science Inc, 2003) Zoghi, M; Gurgun, C; Yavuzgil, O; Turkoglu, I; Kultursay, H; Akilli, A; Akin, M; Turkoglu, CBACKGROUND: Although reciprocal ST segment depression (RSTD) in patients with acute inferior myocardial infarction is a common electrocardiogram finding, its significance is not yet established. In this prospective study, the relationship between RSTD and the extent of coronary artery disease (CAD) was investigated. PATIENTS AND METHODS: One hundred eighty-eight patients with acute inferior myocardial infarction who received thrombolytic therapy were enrolled in this study. The magnitude and location of ST segment depression in noninfarcted leads and the maximum ST segment elevation (STEmax) in inferior leads were measured. All patients were divided into two main groups according to the presence of RSTD and five subgroups according to the location of RSTD, the maximum RSTD and the STEmax. The coronary angiography was performed in all patients 28 4 days after acute myocardial infarction. RESULTS: There were no significant differences in the proportion of coronary disease risk factors in patients with, versus those without, RSTD (P=0.6). Multivessel CAD was present in 63 of the 108 (58%) patients with RSTD and in 32 of the 80 (40%) patients with no RSTD (P=0.02). According to the location of reciprocal changes, multivessel disease was present in significantly more patients with anterior RSTD concomitant with or without lateral ST segment depression (P=0.01 and P=0.03, respectively); the proportion of single vessel disease was greater in patients with only lateral RSTD (P=0.02). In addition, the presence of anterior RSTD to a greater magnitude than the STEmax in inferior myocardial infarction increases the likelihood of multivessel disease (P=0.006). CONCLUSIONS: The presence of RSTD during an acute inferior myocardial infarction correlates with the presence of multivessel CAD and may not be only an electrical phenomenon.Öğe Association between periodontal disease and acute myocardial infarction(Amer Acad Periodontology, 2000) Emingil, G; Buduneli, E; Aliyev, A; Akilli, A; Atilla, GBackground: Coronary heart disease is the leading cause of morbidity and mortality throughout the world. Well-known risk factors independently or combined participate in both myocardial infarction and atherosclerosis. Recent data have shown that viral and bacterial infections may also contribute to the acute thromboembolic events. The aim of the present study was to investigate the possible association between periodontal health and coronary heart disease in patients with acute myocardial infarction and chronic coronary heart disease. Methods: A total of 120 patients, 60 with acute myocardial infarction (AMI) and 60 with chronic coronary heart disease (CCHD) were included in this study. The patients in the AMI group (50 men and 10 women; mean age 53.8 +/- 9.5 years) were admitted to the Department of Cardiology, University Hospital of Ege because of AMI. The CCHD patients group (42 men and 18 women; mean age 58.5 +/- 11.6 years) had no documented history of recent acute coronary events. All patients were clinically examined and completed a medical questionnaire. Missing teeth, restorations, probing depth (PD) and bleeding on probing (BOP) were recorded. Blood samples were taken on admission for measurements of serum total cholesterol, triglycerides, high density lipoprotein cholesterol (HDL-cholesterol), low density lipoprotein cholesterol (LDL-cholesterol), and fasting blood glucose level. Sample proportions were compared by chi square test, quantitative variables with Student t test. The relation of clinical parameters and conventional risk factors to AMI was assessed with logistic regression analysis. Results: The number of sites with PD greater than or equal to4 mm, the percentage of sites exhibiting BOP, smoking status, total cholesterol, LDL-cholesterol, and triglycerides were statistically different between AMI and CCHD groups (P < 0.05). Logistic regression analysis showed that the percentage of sites exhibiting BOP, the number of sites with PD 4, the number of restorations, smoking status, and triglycerides levels were significantly associated with AMI (P < 0.05). Conclusions: The results of this study indicate that periodontal disease may be associated with acute myocardial infarction. To our knowledge, this is the first study that reports the importance of periodontal health in the occurrence of acute myocardial infarction in a Turkish population. We propose that prospective randomized studies are needed to determine whether periodontal disease is a risk factor in the occurrence of acute myocardial infarction.Öğe The effect of cholesterol lowering therapy with atorvastatin on flow-mediated vasodilatation in patients with hypercholesterolaemic coronary artery disease(W B Saunders Co Ltd, 2000) Ercan, E; Gurgun, C; Ceyhan, C; Zoghi, M; Akilli, A; Payzin, S; Can, L; Akin, M; Turkoglu, CÖğe Effect of coronary balloon angioplasty on plasma soluble P-selectin levels.(Excerpta Medica Inc, 1999) Kultursay, H; Kayikcioglu, M; Can, L; Payzin, S; Akilli, A; Turkoglu, CÖğe The effect of exercise on P-wave and QT dispersion in coronary artery disease: an angiographic correlation(W B Saunders Co Ltd, 2000) Zoghi, M; Gurgun, C; Ozerkan, F; Ercan, E; Yavuzgil, O; Akilli, A; Payzin, S; Turkoglu, C; Akin, MÖğe The effect of two different pacing modes on global left-ventricular performance in patients with atrioventricular block: a tissue Doppler echocardiography study(W B Saunders Co Ltd, 2003) Zoghi, M; Yavuzgil, O; Nalbantgil, S; Ozerkan, F; Akilli, A; Turkoglu, C; Kultursay, H; Akin, MÖğe The effect of two different pacing modes on global left-ventricular performance in patients with atrioventricular block: a tissue Doppler echocardiography study(W B Saunders Co Ltd, 2003) Zoghi, M; Yavuzgil, O; Nalbantgil, S; Ozerkan, F; Akilli, A; Turkoglu, C; Kultursay, H; Akin, MÖğe Glycoprotein IIb/IIIa antagonists and inflammation a new effect mechanism in patients with unstable angina pectoris(W B Saunders Co Ltd, 2002) Ercan, E; Bozdemir, H; Ceyhan, C; Tekten, T; Onbasi, A; Altugoglu, I; Bozdemir, G; Akilli, AÖğe Mitral Balloon Valvuloplasty With Transesophageal Echocardiography Without Using Fluoroscopy(Wiley-Liss, 1992) Kultursay, H; Turkoglu, C; Akin, M; Payzin, S; Soydas, C; Akilli, ABalloon mitral valvuloplasty with Inoue technique was performed in two group of patients. In group I (n = 40) valvuloplasty was performed under fluoroscopy without using echocardiography, whereas in group II (n = 13) valvuloplasty was performed under the guidance of transesophageal echocardiography alone, without using fluoroscopy. Patients in two groups were comparable with regard to clinical variables and hemodynamic parameters. Two female patients in group II were pregnant. Transmitral pressure gradient decrease did not differ significantly between two groups (pressure gradient: 17 +/- 5 to 4 +/- 1 in group I and 15 +/- 4 to 3 +/- 1 mm Hg in group II). Mitral valvular area increase was also not different in two groups (1.09 +/- 0.2 cm2 to 2.3 +/- 0.5 cm2 in group I and 0.9 +/- 0.2 to 2 +/- 0.3 cm2 in group II). In 14 cases from group I and 2 cases from group II mitral regurgitation increased after valvuloplasty (p < .05). Left atrial perforation occurred in one patient from group I and 2 patients from group II. In conclusion, mitral balloon valvuloplasty under transesophageal echocardiographic guidance alone is a safe and effective procedure in the treatment of mitral stenosis.Öğe Occlusion of a large coronary to pulmonary communication with coil embolization technique(Health Management Publicationsinc, 1997) Kultursay, H; Can, L; Memis, A; Akilli, A; Payzin, S; Akin, M; Altintig, A; Turkoglu, CÖğe QT dispersion in patients with different etiologies of left ventricular hypertrophy: the significance of QT dispersion in endurance athletes(Elsevier Sci Ireland Ltd, 2002) Zoghi, M; Gurgun, C; Yavuzgil, O; Akilli, A; Turkoglu, C; Kultursay, H; Akin, MLeft ventricular hypertrophy (LVH) increases the risk of ventricular arrhythmias and sudden death and has a significant effect on total cardiovascular mortality. QT dispersion (QTd) is a measure of inhomogeneous repolarization and is used as an indicator of arrhythmogenicity. In this study we detected QTd in patients with different etiologies of left ventricular hypertrophy and the effect of LVH in QTd on endurance athletes. The study group consisted of 147 white male subjects with 3 different etiologies of LVH and 30 healthy male individuals. The underlying etiologies of LVH were essential hypertension, valvular aortic stenosis and long-term training (athletic heart). QTd was measured by surface electrocardiogram and Bazett's formula was used to correct QTd for heart rate (QTcd). Left ventricular mass was determined by transthoracic echocardiography and left ventricular mass index was calculated in relation to body surface area. The QTcd was significantly higher in patients with pathological LVH (due to hypertension and aortic stenosis) than in the athletes' group (physiological LVH) and healthy subjects (P<0.05). The magnitude of QTcd was similar between athletes and the control group (P=0.6). The difference of QTcd between the groups with pathological LVH was not statistically significant (P=0.1). In conclusion; the increasing of QT dispersion is associated with only pathological conditions of LVH. The left ventricular hypertrophy has not a negative effect in QT dispersion on endurance athletes. The measurement of QT dispersion may be a non-invasive useful method for screening additional pathological conditions in endurance athletes. (C) 2002 Elsevier Science Ireland Ltd. All rights reserved.Öğe A rare indication for stenting: Persistent coronary artery spasm(Springer Verlag, 1996) Kultursay, H; Can, L; Payzin, S; Turkoglu, C; Altintig, A; Akin, M; Akilli, AA 34-year-old man presenting with angina both at rest and on exertion was investigated. He developed severe ST segment elevation and a brief period of ventricular tachycardia during an exercise tolerance test. On coronary angiography, 60% fixed luminal narrowing was observed in the proximal left anterior descending coronary artery and a severe spasm developed at this site, leading to temporary total occlusion of the vessel. Successful coronary angioplasty (PTCA) was performed on this lesion, with a residual 15% narrowing. However, the patient had a recurrence of angina 3 weeks later, despite being administered high doses of nitrate and calcium antagonist. During control angiography, the lesion severity was unchanged, but spasm developed again following contrast injection. At this time, a Palmaz-Schatz stent was implanted. Calcium antagonist, nitrate, Ticlopidine and low molecular weight heparin therapy was started. There was no recurrence of symptoms during a 3-month follow-up. The exercise tolerance test, and myocardial perfusion scintigraphy findings were normal and the stent was patent without restenosis at the end of the 3-month follow-up. Intracoronary stent implantation for persistent coronary spasm refractory to conventional medical therapy can be considered a feasible and attractive treatment modality for the control of symptoms.Öğe Response of in-vitro platelet aggregation induced by adenosine diphosphate in stable angina pectoris with essential hypertension(W B Saunders Co Ltd, 2001) Sagcan, A; Omay, SB; Akilli, A; Turkoglu, C; Akin, MÖğe Stenting of myocardial bridging(Health Management Publicationsinc, 1997) Akilli, A; Kultursay, H; Akin, M; Payzin, S; Can, L; Altintig, A; Turkoglu, CÖğe Successful balloon angioplasty of native aortic coarctation in a young adult with refractory hypertension(Elsevier Science Inc, 2002) Akin, M; Ozerkan, F; Akilli, A; Onder, MR; Turkoglu, CControversy exists with regard to the role of balloon angioplasty in the treatment of native aortic coarctation. Recent data and studies have showed that percutaneous balloon angioplasty is a safe and effective treatment for aortic coarctation. We report a young adult with aortic coarctation who has been treated with successful balloon angioplasty. Am J Hypertens 2002;15:1015-1018 (C) 2002 American Journal of Hypertension, Ltd.Öğe Takayasu arteritis in Turkey(Elsevier Sci Ireland Ltd, 1996) Turkoglu, C; Memis, A; Payzin, S; Akin, M; Kultusay, H; Akilli, A; Can, L; Altintig, ATakayasu arteritis is a non-specific inflammatory process of unknown etiology affecting the aorta and its branches. A retrospective study was done in 14 patients diagnosed as Takayasu arteritis. Eleven patients were female and three were male. Ages ranged from 12 to 30 years. Seven patients had type I arteritis, three patients type II arteritis, and four patients type III Takayasu arteritis. Successful angioplasty was performed in five cases.Öğe Takayasu arteritis in Turkey(Elsevier Sci Ireland Ltd, 1996) Turkoglu, C; Memis, A; Payzin, S; Akin, M; Kultusay, H; Akilli, A; Can, L; Altintig, ATakayasu arteritis is a non-specific inflammatory process of unknown etiology affecting the aorta and its branches. A retrospective study was done in 14 patients diagnosed as Takayasu arteritis. Eleven patients were female and three were male. Ages ranged from 12 to 30 years. Seven patients had type I arteritis, three patients type II arteritis, and four patients type III Takayasu arteritis. Successful angioplasty was performed in five cases.Öğe Untitled(Health Management Publicationsinc, 1998) Akilli, A
