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    Comparação dos efeitos de dexmedetomidina administrada em dois momentos diferentes para lesão de isquemia/reperfusão renal em ratos
    (Sociedade Brasileira de Anestesiologia, 2014) Gonullu E.; Ozkardesler S.; Kume T.; Duru L.S.; Akan M.; Guneli M.E.; Ergur B.U.; Meseri R.; Dora O.
    [No abstract available]
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    Comparison of two different enteral nutrition protocol in critically ill patients
    (AVES Ibrahim Kara, 2016) Büyükçoban S.; Akan M.; Koca U.; Eğlen M.Y.; Çiçeklioğlu M.; Mavioğlu Ö.
    Objective: In this study, two enteral nutrition protocols with different gastric residual volumes (GRVs) and different monitoring intervals were compared with respect to gastrointestinal intolerance findings in intensive care unit (ICU) patients. Methods: The study was carried out prospectively in 60 patients in the anaesthesiology and reanimation ICU under mechanical ventilation support, who were scheduled to take enteral feeding. Patients were sequentially divided into two groups: Group 1, GRV threshold of 100 mL, and monitoring interval of 4 hours, and Group 2, GRV threshold of 200 mL, monitoring interval of 8 hours. To test the significant difference between the groups, Student’s t test, chi-square text and Fisher exact test were used. Results: In Group 1, 3.3% vomiting, 6.6% diarrhoea was observed; in Group 2, 16.6% vomiting, 10% diarrhoea. In terms of total intolerance (vomiting and/or diarrhoea) of the two groups, the incidence was significantly higher in Group 2 (33.3%) than in Group 1 (10%) (p=0.02). Conclusion: According to the results of the study, a lower gastrointestinal intolerance rate was detected in the GRV threshold 100 mL, monitoring interval for 4 hours protocol (Group 1) than in GRV threshold 200 mL, monitoring interval for 8 hours protocol (Group 2); Group 1 may be preferred renovation. © 2016 by Turkish Anaesthesiology and Intensive Care Society.
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    Comparison of two different spinal anesthesia techniques using levobupivacaine in perianal surgery [Perianal cerrahide levobupivakain kullani{dotless}lan i·ki degişik spinal anestezi tekniginin karşi{dotless}laşti{dotless}ri{dotless}lmasi{dotless}]
    (Turkiye Klinikleri, 2011) Özkardeşler S.; Akan M.; Karci A.; Alaygut E.; Özzeybek D.; ÖztekIn S.; MeserI R.; Elar Z.
    Objective: General or spinal anesthesia, caudal block, local anesthesia or combination of these techniques may be used for anorectal surgery. The best anesthetic technique and medications are still debated. This study was performed to compare the feasibility of the two spinal anesthetic techniques, namely, saddle block and low spinal anesthesia using plain levobupivacaine in elective perianal surgery. Material and Methods: Fourty ASA (American Society of Anesthesiologists) I-III patients were randomized to receive either saddle block (Group 1) or low spinal anesthesia (Group 2) with 1.5 mL plain levobupivacaine. In both groups, the degree of motor and sensory block, peri- and postoperative side effects, patient and surgeon satisfaction, analgesic requirements as well as durations of anesthesia, surgery and postanesthesia care unit were recorded. Results: The median level of sensorial block was significantly higher in Group 2 (p= 0.007). The sensorial block remained at sacral dermatomes in 35% of patients in Group 1 and in none of the patients in Group 2 (p= 0.008). Bromage scores were "0" in 70% and 21.1% of patients in Group 1 and Group 2, respectively (?2: 9.39, p= 0.002). Seventeen patients in Group 1 and seven patients in Group 2 achieved fast tracking criteria in the operating room and were able to bypass the postanesthesia care unit (?2: 11.493, p= 0.001). Conclusion: Saddle block with plain levobupivacaine used for perianal surgery resulted in absence or less motor block, less admission to postanesthesia care unit, faster recovery when compared to low spinal anesthesia; however side effects, patient and surgeon satisfaction were comparable between the groups. © 2011 by Türkiye Klinikleri.
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    Effects of blood products on nosocomial infections in liver transplant recipients
    (2013) Ozkardesler S.; Avkan-Oguz V.; Akan M.; Unek T.; Ozbilgin M.; Meseri R.; Cimen M.; Karademir S.
    Objectives: Infection is the most severe complication after an organ transplant. Blood cell transfusion is an independent risk factor for adverse events, including infection in the recipient. This study sought to evaluate the effect of blood product transfusions on nosocomial infections in liver transplant patients. Materials and Methods: Patients who underwent a liver transplant at our hospital between 2003 and 2010 were recruited for this study. Exclusion criteria were incomplete records, patients who were hospitalized for more than 48 hours during the 4 weeks before transplant, and pediatric transplants. Incidence of nosocomial infections, which were defined as infections occurring within 30 days after transplant was the primary endpoint. Results: The incidence of nosocomial infections was 28.7%. The number of transfusions of packed red blood cells and fresh frozen plasma was significantly higher in patients with nosocomial infection compared with patients without nosocomial infection (P =.018 and P =.039). Blood products dose-dependently contributed to nosocomial infections. Transfusions of ? 7.5 units of red blood cells (odds ratio: 2.8) or ? 12.5 units of fresh frozen plasma (odds ratio: 3.27) were associated with nosocomial infections (P =.042 and P =.015). The infection-related mortality rate was 10.3%. Conclusions: Blood product transfusions are associated with an increased rate of nosocomial infections, which contributes to higher morbidity and mortality. © Başkent University 2013. Printed in Turkey. All Rights Reserved.
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    Evaluation of education, attitude, and practice of the Turkish anesthesiologists in regional block techniques
    (Kowsar Medical Publishing Company, 2013) Baydar H.; Duru L.S.; Ozkardesler S.; Akan M.; Meseri R.D.; Karka G.
    Background: The demand for regional blocks from both patients and surgeons has significantly increased in anesthesia practice during the last 30 years. Although the studies show that the complications are rare, regional blocks still have serious difficulties which can be prevented by training programs. Objectives: The purpose of this study was to determine the factors affecting the educational methods, attitude and practice of the Turkish anesthesiologists in regional blocks during and following residency programs. Patients and Methods: Anesthesiologists were asked to answer a questionnaire. Educational proficiency was determined by at least 50 spinal, 50 epidural and 50 peripheral block applications during residency. Specialists were asked for the numbers of spinal, epidural and peripheral blocks (PBs) they applied in 2009. The mean and median values were calculated. Results: One hundred and eighty-eight anesthesiologists (84.3 %) agreed to participate in the study. While all participants had made their first attempts in neuraxial blocks (NBs) when they were residents, this ratio was detected as 96.8% for PBs. All participants learned neuraxial and PBs on patients in the operating theater. Education proficiency ratios for spinal, epidural and PBs were 98.1 %, 92.5 % and 62.3 %, respectively. Age, perception of adequate training, nerve block rotation, adequate application in education, following innovations were the factors which significantly affected the number of PBs in practice according to univariate analysis. The participants who consider their applications on NBs were adequate (P = 0.029) and the ones working in state or private hospitals (P = 0.017), applied NBs significantly above the median number. Conclusions: Anesthesiologists had adequate education and practice of NB applications but a significant proportion of participants (51.8%) lacked both in PBs applications. We believe that NBs are more easily learned than PBs during residency training program. © 2013 Iranian Society of Regional Anesthesia and Pain Medicine (ISRAPM); Published by Kowsar Corp.