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Öğe Amniotic membrane transplantation in surgical management of ocular surface squamous neoplasias: long-term results(Nature Publishing Group, 2014) Palamar, M.; Kaya, E.; Egrilmez, S.; Akalin, T.; Yagci, A.Objective To evaluate the long-term efficacy of amniotic membrane transplantation for ocular surface reconstruction in the surgical management of ocular surface squamous neoplasia (OSSN). Methods OSSN in 21 patients (7 female, 14 male patients) was managed with excisional biopsy, cryotherapy, corneal epitheliectomy with absolute alcohol application when the cornea is involved, lamellar sclerectomy and adjunctional absolute alcohol application to the base when episclera is involved, and ocular surface reconstruction with cryopreserved amniotic membrane transplantation. Tumor control and complications were evaluated. Results The mean age of the patients was 62.42 +/- 20.9 (range, 16-84). The average diameter of the base of the tumors was 13.1 +/- 4.8 (range, 9-21) mm and complete removal was achieved in all cases as revealed histopathologically. Ocular surface healing was achieved in all cases. At the postoperative period, limbal stem cell deficiency in three eyes and mild symblepharon in one eye were detected. In a mean follow-up of 30.95 +/- 18.8 (range, 13-75) months, no recurrence was detected. Conclusion For large or multifocal conjunctival tumors, the reconstruction of ocular surface and fornix is challenging. The amniotic-membrane use to repair conjunctival defects larger than 10 mm is a safe and effective technique with minimal complications allowing surgeons to make large enough excisions.Öğe Anaplastic astroblastoma of childhood: aggressive behavior(Springer, 2009) Kantar, M.; Ertan, Y.; Turhan, T.; Kitis, O.; Anacak, Y.; Akalin, T.; Ersahin, Y.; Cetingul, N.Objective Astroblastoma is an unusual brain tumor in childhood. Tumor usually arises from cerebral hemispheres. This large tumor is well-demarcated, lobulated, solid or cystic, and therefore, may resemble glioblastoma. Histopathologically, there are two types of astroblastoma: well-differentiated (low-grade) or anaplastic (high-grade). In low-grade astroblastoma, treatment of choice is complete excision. This type of tumor usually does not recur. However, anaplastic tumors can recur despite surgery, radiation, and chemotherapy and may be problematic for clinician. Case Report A 7-year-old female patient presented with an acute onset of vomiting and seizure. Magnetic resonance imaging study revealed a large mass in the left parietooccipital region. She underwent total excision of the tumor. Histopathologically, the tumor was an anaplastic astroblastoma. Her adjuvant treatment was planned to consist of radiation therapy and cisplatin-based chemotherapy. However, the tumor recurred early in the course, and she died 18 months after diagnosis. Conclusion High-grade astroblastomas behave like glioblastoma, as emphasized in this case report. Local control of this type of tumor seems difficult despite surgery, radiation therapy, and cisplatin-based chemotherapy.Öğe Anaplastic astroblastoma of childhood: aggressive behavior(Springer, 2009) Kantar, M.; Ertan, Y.; Turhan, T.; Kitis, O.; Anacak, Y.; Akalin, T.; Ersahin, Y.; Cetingul, N.Objective Astroblastoma is an unusual brain tumor in childhood. Tumor usually arises from cerebral hemispheres. This large tumor is well-demarcated, lobulated, solid or cystic, and therefore, may resemble glioblastoma. Histopathologically, there are two types of astroblastoma: well-differentiated (low-grade) or anaplastic (high-grade). In low-grade astroblastoma, treatment of choice is complete excision. This type of tumor usually does not recur. However, anaplastic tumors can recur despite surgery, radiation, and chemotherapy and may be problematic for clinician. Case Report A 7-year-old female patient presented with an acute onset of vomiting and seizure. Magnetic resonance imaging study revealed a large mass in the left parietooccipital region. She underwent total excision of the tumor. Histopathologically, the tumor was an anaplastic astroblastoma. Her adjuvant treatment was planned to consist of radiation therapy and cisplatin-based chemotherapy. However, the tumor recurred early in the course, and she died 18 months after diagnosis. Conclusion High-grade astroblastomas behave like glioblastoma, as emphasized in this case report. Local control of this type of tumor seems difficult despite surgery, radiation therapy, and cisplatin-based chemotherapy.Öğe Blue rubber bleb nevus syndrome: a case report with dermatoscopic features(Wiley-Blackwell, 2011) Turk, B. G.; Turkmen, M.; Karaarslan, I. K.; Aydogdu, S.; Akalin, T.; Ozdemir, F.Öğe Can amyloid patterns at salivary gland biopsies give clues for amyloidosis subtyping?(Springer, 2017) Bingul, K. B.; Yaman, B.; Kumbaraci, B. Sarsik; Akalin, T.; Kabasakal, Y.; Sen, S.Öğe A case of bullous pemphigoid clinically mimicking subcorneal pustular dermatosis(Wiley, 2009) Dereli, T.; Karaca, N.; Karaarslan, I. Kilinc; Akalin, T.; Alper, S.Öğe Cutaneous histopathological findings in systemic amyloidosis(Springer, 2022) Yaman, B.; Gomez Gonzalez, C. A.; Acar, A.; Akalin, T.; Kumbaraci, B. Sarsik; Celtik, A.; Sen, S.[No Abstract Available]Öğe Cutanosis amyloidosis: A study with Tioflavin-t and Congo-red staining(Springer, 2016) Igde, B.; Yaman, B.; Turk, B. Gerceker; Akalin, T.; Sen, S.Öğe Dermoscopic features in fungal melanonychia(Wiley-Blackwell, 2015) Karaarslan, I. Kilinc; Acar, A.; Aytimur, D.; Akalin, T.; Ozdemir, F.BackgroundData on the dermoscopic features of fungal melanonychia are limited. AimTo identify the dermoscopic features of fungal melanonychia. MethodsWe reviewed patient files, clinical history and dermoscopic images of all cases with a diagnosis of fungal melanonychia seen at our dermoscopy unit within the past year. ResultsIn total, 14 cases with 20 involved nails were reviewed. The most common type of melanonychia was melanonychia striata (7/20). Multicoloured pigmentation was observed in 19 of the nails. The main dermoscopic pattern was homogeneous pigmentation; however, black pigmented aggregates, presenting as either coarse granules or pigmented clumps, accompanied this homogeneous pigmentation in 16 lesions. Matt black pigmentation, matt white pigmentation, yellow to brown pigmentation, black reverse triangle (wider at the distal than the proximal end), superficial transverse striation and blurred appearance were the other features. ConclusionsWe have identified a number of dermoscopic features appearing in fungal melanonychia, which should help in diagnosis of this disease.Öğe Dermoscopic features in fungal melanonychia(Wiley-Blackwell, 2015) Karaarslan, I. Kilinc; Acar, A.; Aytimur, D.; Akalin, T.; Ozdemir, F.BackgroundData on the dermoscopic features of fungal melanonychia are limited. AimTo identify the dermoscopic features of fungal melanonychia. MethodsWe reviewed patient files, clinical history and dermoscopic images of all cases with a diagnosis of fungal melanonychia seen at our dermoscopy unit within the past year. ResultsIn total, 14 cases with 20 involved nails were reviewed. The most common type of melanonychia was melanonychia striata (7/20). Multicoloured pigmentation was observed in 19 of the nails. The main dermoscopic pattern was homogeneous pigmentation; however, black pigmented aggregates, presenting as either coarse granules or pigmented clumps, accompanied this homogeneous pigmentation in 16 lesions. Matt black pigmentation, matt white pigmentation, yellow to brown pigmentation, black reverse triangle (wider at the distal than the proximal end), superficial transverse striation and blurred appearance were the other features. ConclusionsWe have identified a number of dermoscopic features appearing in fungal melanonychia, which should help in diagnosis of this disease.Öğe Dermoscopic features in fungal melanonychia(Wiley-Blackwell, 2015) Karaarslan, I. Kilinc; Acar, A.; Aytimur, D.; Akalin, T.; Ozdemir, F.BackgroundData on the dermoscopic features of fungal melanonychia are limited. AimTo identify the dermoscopic features of fungal melanonychia. MethodsWe reviewed patient files, clinical history and dermoscopic images of all cases with a diagnosis of fungal melanonychia seen at our dermoscopy unit within the past year. ResultsIn total, 14 cases with 20 involved nails were reviewed. The most common type of melanonychia was melanonychia striata (7/20). Multicoloured pigmentation was observed in 19 of the nails. The main dermoscopic pattern was homogeneous pigmentation; however, black pigmented aggregates, presenting as either coarse granules or pigmented clumps, accompanied this homogeneous pigmentation in 16 lesions. Matt black pigmentation, matt white pigmentation, yellow to brown pigmentation, black reverse triangle (wider at the distal than the proximal end), superficial transverse striation and blurred appearance were the other features. ConclusionsWe have identified a number of dermoscopic features appearing in fungal melanonychia, which should help in diagnosis of this disease.Öğe Desmoid type fibromatosis: Clinicopathologic analysis of 113 cases(Springer, 2017) Buyuktalanci, E.; Yaman, B.; Akalin, T.Öğe DO EXPRESSIONS OF OLIG2, PTEN AND DMBT1 GENES PLAY A ROLE IN HIGH-GRADE GLIOMAS PROGRESSION?(Duke Univ Press, 2008) Avci, C. Biray; Oktar, N.; Dalbasti, T.; Yilmaz, S.; Dodurga, Y.; Dogan, Z. O.; Numanoglu, S.; Akalin, T.; Gunduz, C.Öğe Dysembryoplastic Neuroepithelial Tumour of Childhood: EGE University Experience(Wiley-Blackwell, 2016) Sahin, A.; Kantar, M.; Turhan, T.; Akalin, T.; Kitis, O.; Bolat, E.; Eraslan, C.; Ertan, Y.; Serdaroglu, G.; Cetingul, N.; Anacak, Y.; Mutluer, S.Öğe Eruptive disseminated Spitz naevi: dermatoscopic features(Wiley, 2009) Karaarslan, I. Kilinc; Ozdemir, F.; Akalin, T.; Ozturk, G.; Turk, B. G.; Kandiloglu, G.Eruptive disseminated Spitz naevi is a rarely reported condition. Although the dermatoscopic features of nondisseminated, solitary forms of Spitz naevi are well known, there are no reports describing the dermatoscopic features of eruptive disseminated variant. We report an additional case and describe the dermatoscopic features. Two patterns were observed. In all pink lesions, the vascular pattern was seen, composed of dotted, linear or comma-like vessels located at the centre of the meshes of the reticular depigmentation. In all brown lesions, we observed only the reticular pattern, which is quite interesting as the reticular pattern is a rare feature of Spitz naevi. This observation may be a special feature particularly seen in the eruptive disseminated variant. A superficial black network also accompanied reticular pattern in some lesions. In dichromatic lesions, both patterns were observed in different areas of the body.Öğe Eruptive disseminated Spitz naevi: dermatoscopic features(Wiley, 2009) Karaarslan, I. Kilinc; Ozdemir, F.; Akalin, T.; Ozturk, G.; Turk, B. G.; Kandiloglu, G.Eruptive disseminated Spitz naevi is a rarely reported condition. Although the dermatoscopic features of nondisseminated, solitary forms of Spitz naevi are well known, there are no reports describing the dermatoscopic features of eruptive disseminated variant. We report an additional case and describe the dermatoscopic features. Two patterns were observed. In all pink lesions, the vascular pattern was seen, composed of dotted, linear or comma-like vessels located at the centre of the meshes of the reticular depigmentation. In all brown lesions, we observed only the reticular pattern, which is quite interesting as the reticular pattern is a rare feature of Spitz naevi. This observation may be a special feature particularly seen in the eruptive disseminated variant. A superficial black network also accompanied reticular pattern in some lesions. In dichromatic lesions, both patterns were observed in different areas of the body.Öğe Expression of c-KIT in malignant melanoma subtypes: An immunohistochemical study(Springer, 2017) Yaman, B.; Soyluer, U.; Akalin, T.Öğe Folliculotropic T-cell lymphocytosis as an associated finding in mycosis fungoides(Wiley, 2009) Karaarslan, I. Kilinc; Turkmen, M.; Ertekin, B.; Akalin, T.; Ozturk, G.Öğe Gastrointestinal stromal tumours accompanying other neoplasms(Springer, 2014) Calik, M.; Doganavsargil, B.; Caliskan, C.; Firat, O.; Sezak, M.; Akalin, T.Öğe Hobnail haemangioma: dermatoscopic findings facilitating the differential diagnosis(Wiley-Blackwell Publishing, Inc, 2009) Ertam, I.; Akalin, T.; Unal, I.; Ozdemir, F.
