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Öğe Diverse effects of ganoderma lucidum in combination with tamoxifen citrate and doxorubicin in MCF-7 breast cancer cells(Wiley-Blackwell, 2016) Atay, S.; Ak, H.; Kalmis, E.; Kayalar, H.; Aydin, H. H.Öğe GENOME-WIDE COPY NUMBER VARIATION ANALYSIS IN IDIOPATHIC INTELLECTUAL DISABILITY/MULTIPLE CONGENITAL ANOMALIES(Medecine Et Hygiene, 2014) Pariltay, E.; Durmaz, A.; Durmaz, B.; Aykut, A.; Onay, H.; Ak, H.; Aydin, H. H.; Özkınay, Ferda; Cogulu, O.Genome-wide copy number variation analysis in idiopathic intellectual disability/multiple congenital anomalies: New array technologies have facilitated the analysis of submicroscopic chromosomal imbalances and structural variants. Copy number variation (CNV) analysis can reveal genetic imbalances in up to 10 % of cases involving intellectual disability (ID), with or without multiple congenital anomalies (MCA). Here we present 4 cases, diagnosed by CNV analysis using Affymetrix Genome Wide Human SNP 6.0 array, and their parents. CNVs ranging from 18 to 196 per subject, with a size range of 100kb-6093kb, were detected in all cases. One case revealed inherited CNVs, whilst de novo ins/dels were found in the other three which may be causative factors in the development of clinical pictures. Microarray technology may help to reveal the etiology of ID and is a potentially useful diagnostic tool for patients with ID/MCA.Öğe Investigating the effects of Hericium erinaceus extracts on telomerase activity in MCF-7 cells(Wiley-Blackwell, 2016) Gencalp, D.; Ak, H.; Aydin, H. H.; Kalmis, E.; Kayalar, H.Öğe Investigation of the effects of GW8510 pharmacological inhibitor on in vitro pancreatic cancer model(Wiley, 2019) Gencalp, D.; Ak, H.; Atay, S.; Aydin, H. H.[No abstract available]Öğe IS OVERACTIVE BLADDER MICROVASCULATURE DISEASE A COMPONENT OF SYSTEMIC ATHEROSCLEOROSIS?(Wiley, 2017) Yeniel, A. O.; Ergenoglu, A. M.; Meseri, R.; Kismali, E.; Kavukcu, G.; Ari, A.; Aydin, H. H.; Ak, H.; Atay, S.; Itil, I. M.
