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    The effect of cigarette smoke on the plasma piroxicam concentrations in rats
    (1990) Lermioglu F.; Berkan T.; Yasa M.; Kerry Z.; Yalçinkaya C.; özer A.
    Abstract— The plasma concentration of unchanged piroxicam has been determined at 15, 30, 60 and 90 min after 10 mg kg-1 oral administration of the drug to rats exposed to cigarette smoke or pretreated with phenobarbitone, 3,4-benzpyrene or ethanol. Plasma piroxicam concentrations decreased in rats pretreated with phenobarbitone, 3,4-benzpyrene and ethanol and in rats 24 h after exposure to cigarette smoke. 1990 Royal Pharmaceutical Society of Great Britain