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Öğe Biosensors: Fundamentals, emerging technologies, and applications(CRC Press, 2022) Özkan S.A.; Uslu B.; Sezgintürk M.K.Biosensors: Fundamentals, Emerging Technologies, and Applications provides insight into the sensing applications of different types of biosensors relating to environmental pollutants, microbiological analysis, and healthcare. It describes state-of-the-art research in biosensors, point of care testing, potential applications, as well as future prospects for biosensors. This book: Presents the essentials that readers need to know to make full use of biosensor technology. Discusses recent perspectives on optical and electrochemical biosensors. Details biosensor types for medical applications. Teaches how to use enzymes for biological recognition in biomarker assays. Proposes innovations in wearable and smart biosensors. This book is aimed at advanced students, researchers, and academics across a broad interdisciplinary field including biochemical, pharmaceutical, and environmental engineering as well as materials science, analytical chemistry, and biosciences. © 2023 Taylor & Francis Group, LLC. All rights reserved.Öğe Breast metastasis: A rare involvement in a male patient with nonsmall cell lung carcinoma [Küçük hücreli dişi akciger karsinomu olan erkek olguda nadir bir tutulum: Meme metastazi](2010) Çetinkaya P.D.; Özkan S.A.; Erer O.F.; Ari G.; Veral A.The breast is one of the uncommon site of metastasis in non-small cell lung cancer. Breast metastasis was detected by breast tissue biopsy and immunohistochemical analysis in a 59 year old male patient who was diagnosed previously as non-small cell lung cancer. We reported this case because it is extremely rare.Öğe In vitro effects of ciprofloxacin, levofloxacin and moxifloxacin on mycobacterium tuberculosis isolates [Mycobacterium tuberculosis kökenleri üzerine siprofloksasin, levofloksasin ve moksifloksasinin in vitro etkinliği](Ankara University, 2018) Yilmaz F.F.; Eraç B.; Ermertcan Ş.; Çavuşoğlu C.; Biçmen C.; Özkan S.A.; Hoşgör Limoncu M.In vitro effects of ciprofloxacin, levofloxacin and Moxifloxacin on Mycobacterium tuberculosis isolates Introduction: Increased tuberculosis prevalence, and isolation of multidrug resistant (MDR) Mycobacterium tuberculosis strains frequently as causative organisms from tuberculosis infections are resulted in increasing need of new anti-tuberculosis drugs. Nowadays, fluoroquinolones known to have fewer side effects than the other drugs used in treatment of tuberculosis are sometimes assessed even as first-line anti-tuberculosis drugs due to their in vitro and in vivo strong activity. It was aimed in this study to investigate phenotypically the fluoroquinolone susceptibility in MDR and non-MDR M. tuberculosis isolates. Materials and Methods: A total of 126 MDR and non-MDR M. tuberculosis isolates from mycobacteriology laboratory of two hospitals in the Aegean Region of Turkey were included in the study. Ciprofloxacin (CIP), levofloxacin (LEV) and moxifloxacin (MXF) susceptibilities were assessed by agar proportion method according to the Clinical and Laboratory Standards Institute (CLSI) recommendations. Results: Twelve (15.2%), 5 (6.3%) and 4 (5.1%) of the MDR M. tuberculosis strains were resistant to CIP, LEV, MXF, respectively [resistance breakpoints (µg/mL); CIP (> 2), LEV (> 1), MXF (> 0.5)] while non-MDR strains were susceptible to CIP, LEV, MXF. Conclusion: Consequently, although high fluoroquinolone susceptibilities were evaluated as a pleasing data in this study, to preserve their efficiency for many years steadily, quinolone usage and resistance increment in MDR M. tuberculosis isolates should be monitored elaborately. © 2018, Ankara University. All rights reserved.