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Öğe Aripiprazole use in children and adolescents: A case series [Çocuk ve gençlerde aripiprazol kullanimi: Olgu serisi](2010) Bildik T.; Özbaran N.B.; Küçükköse M.; Ardiç Ü.A.In children and adolescents, atypical antipsychotics have been largely used to treat aggression, mood instability, and psychosis. There is a growing interest in the use of aripiprazole in children and adolescents with schizophrenia, pervasive developmental disorders, and bipolar disorders. A series of 7 children and adolescents (ages 11-17 years, 5 males) were treated with aripiprazole for different psychiatric disorders. All patients had been treated previously with several psychotropic drugs. Aripiprazole was initiated at a starting dose of 2.5 or 5 mg daily and optimal dosages ranged from 5 to 10 mg daily. Six of the 7 patients appeared to benefit from aripiprazole. Neither extrapyramidal side effects nor agitation was observed in any case. Aripiprazole was well tolerated and effective in our cases and appears to be a safe and efficacious alternative in the child and adolescents. However, prospective clinical trials with a randomized placebo controlled design are needed.Öğe Motor tics due to atomoxetine use: A case report [Atomoksetin kullani{dotless}mi{dotless}na bagli{dotless} motor tikler: Olgu sunumu](Cukurova Univ Tip Fakultesi Psikiyatri Anabilim Dali, 2011) Küçükköse M.; Özbaran N.B.; Köse S.G.Motor tics due to atomoxetine use: a case report The comorbidity ratio of attention deficit and hyperactivity disorder (ADHD) and tic disorders (TD) or Tourette's syndrome (TS) is very high. It is also known that, psychostimulant use in the treatment of ADHD can increase existing tics or cause new tics. Therefore, a selective noradrenaline reuptake inhibitor, atomoxetine, which is effective in the treatment of tics and ADHD symptoms, was introduced into clinical practice as a treatment choice in patients with ADHD and TD/TS comorbidity. However, recently there have been reports about reverse effects of atomoxetine on tics. In this report, we discuss a clinical case that had an increase in existing tic severity and developed new tics during atomoxetine treatment.