Ege Üniversitesi Kurumsal Akademik Arşivi
DSpace@Ege, Ege Üniversitesi tarafından doğrudan ve dolaylı olarak yayınlanan; kitap, makale, tez, bildiri, rapor, araştırma verisi gibi tüm akademik kaynakları uluslararası standartlarda dijital ortamda depolar, Üniversitenin akademik performansını izlemeye aracılık eder, kaynakları uzun süreli saklar ve telif haklarına uygun olarak Açık Erişime sunar.
Güncel Gönderiler
The Relationship of Serum Diabetes Antibodies With the Development of Early Diabetic Retinopathy Findings in Children With Type 1 Diabetes Mellitus
(SLACK Inc., 2024) Korkmaz, Hueseyin Anil; Dogan, Beyza; Devebacak, Ali; Degirmenci, Cumali; Afrashi, Filiz
Purpose:To explore how serum diabetes autoantibodies are related to the development of early diabetic retinopathy in children with type 1 diabetes mellitus. Methods: In this prospective and observational study, 62 patients with type 1 diabetes mellitus who had not yet developed clinical diabetic retinopathy were followed up for at least 5 years. Healthy volunteers aged 10 to 20 years were also included. Insulin, pancreatic islet cells, and glutamic acid decarboxylase (GAD) autoantibodies were measured with an RIA kit at the time of type 1 diabetes mellitus diagnosis. Optical coherence tomography angiography (OCTA) was used to evaluate the foveal avascular zone (FAZ) and parafoveal vascular density (PVD) for the development of early diabetic retinopathy among the groups. Patients'OCTA findings were compared with those of healthy volunteers. The obtained data were analyzed via IBM SPSS Statistics for Windows, version 27.0. Spearman's rank correlation test and regression analysis were performed to determine independent predictors of OCTA and type 1 diabetes mellitus parameters. Results: Eighteen boys and 44 girls with type 1 diabetes mellitus with a median age of 15.6 years (range: 10.08 to 20.88 years) were evaluated. Healthy control participants with a median age of 15.3 years (range: 14.2 to 18.2 years) were also included. The mean FAZ was greater in the type 1 diabetes mellitus group than in the healthy control group (P = .013 and .119, respectively). The mean PVD was significantly lower in the type 1 diabetes mellitus group than in the healthy control group. There was no significant correlation between serum diabetes autoantibodies (GAD and insulin autoantibodies) and FAZ or PVD (FAZ and GAD; r = 0.138, P = .286, FAZ and anti-insulin; r = 0.100, P = .441, PVD and GAD; r =-0.151, P = .24, PVD and anti-insulin; r =-0.087, P = .499). Conclusions: Type 1 diabetes mellitus in children without clinically detectable diabetic retinopathy is associated with impaired retinal microcirculation and irregularities at the FAZ margin. Impaired retinal microcirculation and irregularities were associated with glycated hemoglobin levels in the study group. Thus, studies with larger patient series are needed.
CEMENT TILES IN PUBLIC BUILDINGS OF THE FIRST NATIONAL ARCHITECTURAL MOVEMENT PERIOD: SAMPLES OF İZMİR
(E.U. Printing and Publishing House, 2024) Ozkan Tekneci, Zeynep; Ucar, Aygul
Cement tile is a flooring material used to decorate floors, walls, and fa & ccedil;ades as part of the architectural whole. Besides offering a decorative appearance, cement tiles are easy to clean and hygienic. This tiling material prepared with mixtures of pigmented cement, marble powder, white cement, and other minerals consists of three layers. The decorative, patterned, and pigmented layer is at the bottom during production and creates the top surface at the end of production. This patterned layer is prepared by pouring colored cement into the chambers in the partitioned molds. The other two layers, composed of different contents, facilitate the installation of the tile on the floor. Following the discovery of cement, cement tiles were first produced in France in the mid-19th century and spread to settlements around the Mediterranean and then around the whole world through trade routes. The misunderstanding of the French pronunciation caused this material to be known as " karosiman " in Ottoman times. This material was initially imported to cities such as Istanbul, Izmir, and Mersin, where much of the Ottoman- time Levantine population lived, soon becoming widespread throughout Anatolia and was used in many different building types during the Ottoman period. When examined specifically in the case of Izmir, cement tiles were generally used in residential buildings dating from the late 19th and early 20th centuries. They were also preferred to tile the floors of many public buildings, such as hospitals, schools, inns, cinemas, libraries, banks, and business halls built under the influence of the First National Architectural Movement. The First National Architectural Movement was influential in Turkish architecture between 1908 and 1930, a period that started with the declaration of the Second Constitutional Monarchy and covered important events such as the national struggles and the proclamation of the Republic. The public buildings in Izmir built in the First National Architectural Movement period mostly date to the 1920s. In terms of fa & ccedil;ade design, these buildings are characterized by decorative elements taken from Seljuk and Classical Ottoman architecture. Although the First National Architecture Movement is a style characterized by its fa & ccedil;ade features, it also influenced the interior decoration of the buildings. In parallel with the fa & ccedil;ade features, the use of pointed, flattened, and Bursa-type arches, column capitals with stalactites, and balustrades with interlaced geometric compositions draw attention to the interiors. In these buildings, cement tiles were used as flooring material but have become an element that complements the whole. Seljuk and Ottoman ornamental motifs such as tulips, carnations, multi-armed stars, and geometric interlaces were painted on the cement tiles. The spirit of the period was made to feel from the fa & ccedil;ades to the floors. This article aims to introduce the cement tiles used in the public buildings built during the First National Architecture Movement by considering the motif, color, and form features and the places where they were used and to emphasize their place in the period through samples in Izmir.
The Role of Camel and Donkey Milk in Enhancing Quality Properties and In vitro Antioxidant and Antidiabetic Activity of Strained Yogurt
(Hellenic Veterinary Medical Soc, 2024) Akan, E.; Akgul, F. Yildiz; Karaman, A. D.; Kinik, O.; Ogut, S.; Celebi, M.
With increasing emphasis on health, there has been a growing global demand for functional foods. Due to their various health and therapeutic effects, donkey and camel milk have also gained significance. The potential of these milks to be converted into products needs to be evaluated. In this study, the possibility of using a ratio of 15% and 30% camel and donkey milk together with cow milk in the production of strained yogurt has been evaluated. The physicochemical, microbiological, in vitro antioxidant (2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid (ABTS), Cupric Reducing Antioxidant Capacity (CUPRAC), 2,2-diphenyl-1-picrylhydrazyl (DPPH)) and antidiabetic (alpha-glucosidase inhibitory effect) properties of strained yogurts were evaluated during the 21 day of storage. It was observed that camel and donkey milk containing yogurts coalugum were similar to control yogurt. The addition of 30% donkey milk to cow milk significantly shortened the fermentation time (p<0.05). Throughout the storage period, yogurts containing 15% and 30% donkey milk exhibited the highest levels of lactic acid (p<0.05). The antioxidant activity of yogurt samples varied depending on the storage period and the method used.. Yogurt containing 30% camel milk had significantly higher in vitro antidiabetic activity (p<0.05). In this study, camel and donkey milk, which are claimed to offer health benefits, was tested in yogurt manufacturing. In conclusion, these yogurt products can be included in the functional food category by evaluating various health benefits with in vitro and in vivo trials.
A low-cost electronic and optical system for magnetic hyperthermia experimental studies
(Elsevier, 2024) Ozturk, Yavuz; Yilmaz, Ali Altan; Seymen, Yigit; Harmansah, Coskun
Magnetic hyperthermia is an alternative to treatments such as chemotherapy and radiotherapy that employs the heat generated by magnetic nanoparticles under the influence of a magnetic field to kill cancer cells while ideally causing no harm to healthy tissues. A low-cost magnetic hyperthermia investigation platform with commercially available and easy-to-assemble parts was presented to provide and expand research in this area for a larger scientific community. The magnetic hyperthermia measurement system consists of three main parts: a designed thermally insulated sample holder, a commercial 88 kHz magnetic induction heater, and a custom-built fiber optic based refractometer as temperature sensor. The system was tested with commercial EFH-1 magnetic fluids. Time dependent temperature changes were measured for applied magnetic fields of 3.5 kA/m, 4.8 kA/m, and 6.0 kA/m. The corresponding specific loss power values were calculated as 0.28 W/g, 0.51 W/g, and 0.79 W/g, respectively. Intrinsic loss power of commercial ferrofluid was determined as 0.25 +/- 0.01 nHm2/kg, 2 /kg, found to be comparable to the results of specialized commercial magnetic hyperthermia systems. The results show that the system can easily be used for hyperthermia demonstrations for educational purposes as well as in convenient scientific research with proper calibration.
Quince Powder Increases Antioxidant Activity and Probiotic Survival in Yoghurt
(Faculty Food Technology and Biotechnology, 2024) Cinar, Senay Burak; Unal, Gulfem; Koc, Gulsah Caliskan; Dirim, Safiye Nur; Akalin, Ayse Sibel
Research background. In recent years, there has been a growing interest in incorporating fruit-based additives into yogurt formulations as a means to improve the functionality of the product. This study aims to produce a functional product by incorporating quince, which is rich in fibre, vitamins, minerals and antioxidant activity, into a yoghurt formulation. Experimental approach. The influence of the addition of quince powder (0 (control), 0.5, 1.0 and 1.5 %) on the antioxidant and proteolytic activities and culture viability of probiotic yoghurt was investigated for 28 days. Results and conclusions. The viable counts of yoghurt bacteria and Bifidobacterium lactis BB-12 (R) were above 8 log CFU/g. Higher viability of all bacteria was obtained in yoghurt fortified with 1.5 % quince powder than those of other samples after 14 days. Probiotic yoghurt with added 1.5 % quince powder had the highest proteolytic activity during the last two weeks of storage, while the highest total phenolic content and (2,2-diphenyl-1-picrylhydrazyl) radical (DPPH center dot) scavenging activity were obtained for the same sample throughout the storage period. Noveltyand scientificcontribution. Quince powder supports the health of the digestive system thanks to its high fibre content, while it is also rich in vitamins, minerals and antioxidant activity. These properties emphasise the importance of using quince powder in yoghurt production. This innovation has the potential to provide consumers with a tasty alternative, while at the same time increasing the intake of health-promoting ingredients. Furthermore, such products offer higher nutritional value than conventional yoghurt, offering consumers with a healthier option. Therefore, the production of yoghurt with quince powder can be considered as an important innovation in the field of nutrition and a practice that contributes to increasing health awareness.
