Dogan, EserLevent, Ertuerk2024-08-312024-08-3120242168-8184https://doi.org/10.7759/cureus.57150https://hdl.handle.net/11454/105287Purpose: Transcatheter closure is the first -line treatment option for hemodynamically significant secundum atrial septal defects (ASDs). This study examines our center's experience with this procedure over the last 15 years. Materials and methods: Pediatric patients aged 0-18 years with secundum ASDs who were planned for transcatheter closure in our clinic between January 2007 and January 2023 were retrospectively evaluated. Results: Transcatheter secundum ASD closure was planned for a total of 334 patients during the study period: 191 girls (57.2%) and 143 boys (42.8%). Their mean age was 8.08 +/- 3.9 years, and their mean weight was 30 +/- 15.6 kg. Defect diameter measured transesophageally ranged from 5 to 35 mm, with a mean of 12.56 +/- 4.02 mm. Transesophageal echocardiographic examination revealed a single secundum ASD in 319 patients (95.5%) and multiple secundum ASDs in 15 patients (4.5%). In 11 patients (3.3%), the procedure was terminated before initiating transcatheter ASD closure because of insufficient vena cava rims or a very large or multi -fenestrated defect. The 323 patients (96.7%) who underwent transcatheter ASD closure had a mean pulmonary artery pressure of 15.1 +/- 4.0 mmHg and a mean Qp/Qs ratio of 1.97 +/- 0.56. The procedure failed in four patients (1.3%) because of device embolization (n=2) or the inability to properly position the device (n=2). Major complications other than device embolization observed during or after transcatheter closure included anesthetic -induced respiratory depression (n=1) and total atelectasis of the lung (n=1). No new major complications were detected during the patients' long-term follow-up. Conclusion: With appropriate patient and device selection, transcatheter closure is a safe and effective treatment for secundum ASD and should be the first treatment of choice.en10.7759/cureus.57150info:eu-repo/semantics/openAccessTranscatheter Closure DeviceAsd ClosureTranscatheterPediatricAtrial Septal DefectArticle163WOS:00120577270000938681362N/A