Yapali S.Turan I.Ozutemiz O.Tekesin O.2019-10-272019-10-2720140043-5325https://doi.org/10.1007/s00508-014-0610-9https://hdl.handle.net/11454/26095D-penicillamine has long been used in the management of rheumatic diseases due to the effects on inhibition of collagen synthesis. Herein, we report a severe case of esophageal ulcer causing a tight stricture extending through the distal esophagus despite the longterm D-penicillamine treatment in a patient with Wilson’s disease. D-penicillamine would theoretically be expected to contribute to the healing of an esophageal ulcer. However, the drug failed to have a favorable outcome, which is notable and worth reporting. © Springer-Verlag Wien 2014.en10.1007/s00508-014-0610-9info:eu-repo/semantics/closedAccessBalloon dilationD-penicillamineEsophageal strictureEsophageal ulcerPeptic strictureA severe case of esophageal ulcer causing a tight stricture despite long-term D-penicillamine treatment [Ein Fall eines ausgeprägten Ösophagusulkus mit Striktur trotz Langzeittherapie mit D-Penicillamin]Article1262378979125234939Q2