Altay B.KefI A.Tavmergen E.ÇIkIlI N.Semerci B.Goker E.T.2019-10-272019-10-2720020301-1623https://doi.org/10.1023/A:1014425508427https://hdl.handle.net/11454/23062Introduction: Testicular sperm extraction (TESE) is well-defined procedure for surgical sperm retrieval in obstructive and non-obstructive azoospermia. This study was focused on the effectiveness of testicular sperm extraction and intracytoplasmic sperm injection (ICSI) for azoospermic men with different female age subgroups. Materials and methods: A total of 107 men with azoospermia underwent TESE and ICSI treatment. The women were examined in three groups 20-29, 30-34 and 35 years or older. The main outcome in this study was fertilization and pregnancy rates with TESE and ICSI. Results: Spermatozoa were successfully retrieved during 97 of 107 (90.7%) TESE attempts, resulting in the fertilization of 286 of 563 (50.4%) injected metaphase II oocytes. Two hundred and fifty-five of them were transferred (89.8%). The clinical pregnancy rate and ongoing pregnancy rate per embryo transfer were 22.5% and 20.6% respectively. When comparing the fertilization and pregnancy rates, it was observed that women between the ages of 20-29 years had significantly higher pregnancy rates than women over 34 years of age (p < 0.05). Conclusion: The female age is a major factor in determining successful implantation in ICSI.en10.1023/A:1014425508427info:eu-repo/semantics/closedAccessFemale ageFertilization rateIntracytoplasmic sperm injection (ICSI)Testicular sperm extraction (TESE)Article331959912090348Q2