Parlak, YaseminTekin, VolkanMüftüler, Fazilet Zümrüt BiberTopal, GökçenGümüşler, GülAkınlı, MertAvcıbaşı, Uğur2023-01-122023-01-1220212687-475Xhttps://doi.org/10.15671/hjbc.656021https://search.trdizin.gov.tr/yayin/detay/461866https://hdl.handle.net/11454/80283In this study, whey protein was radiolabeled with $Tc-^{99m}$ using the SnCl2 reduction method. The paper electrophoresis technique was done in the radiochromatography studies. SF (saline solution) was used as a suitable mobile phase. At the same time, the labeling yield of ${}^{99m}Tc$WHEY was found to be about 95%. Then, lipophilicity and stability studies were carried out, respectively. Finally, imaging and biodistribution studies were completed using Albino Wistar Rats. In vivo studies showed that ${}^{99m}Tc$WHEY was accumulated in the breast, the ovaria and the pancreas. In conclusion, all results showed that ${}^{99m}Tc$WHEY may be helpful in the diagnosis of the breast, the ovaria and the pancreas in the future.en10.15671/hjbc.656021info:eu-repo/semantics/openAccessArticle493243252461866