Alpan A.S.Yilmaz Ö.Kiliçkaya O.Kara P.Güneş H.S.Özsöz M.Ş.2019-10-262019-10-2620121309-08011309-0801https://doi.org/10.12991/201216420https://hdl.handle.net/11454/18261In this study, synthesis and determination of interaction between DNA and 1H-benzimidazole derivatives has been performed by using electrochemical genosensor technology. Detection of DNA - drug interaction mechanism relies on monitoring Differential pulse voltammetric (DPV) responses of drugs at disposable graphite electrodes (DGEs). Interaction of 7 different benzimidazole derivates between double-stranded (ds) and singlestranded (ss) DNA were observed by changing the voltammetric signals of drugs at the detection limits of 0.62 nM of compound 1, 1.23 nM of 2, 1.26 nM of 3, 1.08 nM of 4, 1.13 nM of 5, 0.69 nM of 6 and 0.42 nM of 7, respectively.en10.12991/201216420info:eu-repo/semantics/closedAccess1H-benzimidazoleDNA-drug interactionElectrochemical genosensorSynthesisArticle1614855N/A