Ersoy, ElifKirazli, TayfunEsassolak, MustafaBilgen, CemBasdemir, Guelcin2019-10-272019-10-2720081305-52671305-5267https://hdl.handle.net/11454/40952OBJECTIVE: Radiotherapy has been an alternative therapy in benign pathologies with epithelial and connective tissue hyperplasia. The aim of this study was to investigate the efficacy of low dose radiotherapy in the inhibition of cholesteatoma in an experimantal cholesteatoma model in rats. MATERIAL AND METHODS: Thirty-five Wistar albino rats were used to form 3 groups: Group I (n=20; bilateral cholesteatoma induction with propylene-glycol), Group 11 (n=10; unilateral cholesteatoma induction with propylene-glycol and unilateral intratympanic saline injection), Group III (n=5, control group without injection). The effect of radiotherapy was evaluated according to the histopathological parameters. RESULTS: The results indicated that low dose radiotherapy was ineffective in the management of cholesteatoma in this histopathological study.eninfo:eu-repo/semantics/closedAccessArticle426976WOS:000259303100002N/AN/A