Enginar H.Unak P.Yurt Lambrecht F.Biber F.Z.2019-10-272019-10-2720040236-57310236-5731https://doi.org/10.1023/B:JRNC.0000027107.43043.37https://hdl.handle.net/11454/27798An estrogen derivative 1-(3, 17-?-estradiolyl propin-1-yl-3-(1,4,8, 11-tetraazacyclotetradecyl)-propanate (ESTACPA) was synthesized. The product was purified by HPLC and characterized by NMR and IR spectroscopy. The synthesized compound was labeled with 99mTc. The biodistribution studies were performed on female Albino Wistar rats. The rats were sacrificed and their organs were removed. The radioactivities of the organs were counted using a gamma-counter. The activity per gram tissue was calculated and time versus activity curves were generated. The 99mTc-ESTACPA uptake by the uterus and ovary such as ER-rich tissues, were observed. The pancreas and stomach also showed a significant uptake.en10.1023/B:JRNC.0000027107.43043.37info:eu-repo/semantics/closedAccessSynthesis of a 99mTc labeled estrogen-derivative and the determination of its radiopharmaceutical potential on ratsArticle2602339349Q2