Cotert, IremAytug, MerveCotert, H. Serdar2025-03-192025-03-192024Çötert, İ., Aytuğ, M., & Çötert, H. S. (2024). Comparative evaluation of desensitizing agents on shear bond strength of zirconia to dentin. ( No. 24).BioMed Central Ltd.1472-6831https://doi.org/10.1186/s12903-024-05106-8https://hdl.handle.net/11454/116797Background The purpose of the study is to evaluate the effect of 7 different desensitizing agents on the shear bond strength (SBS) of zirconia restorations to dentin with a self-adhesive resin cement and determine the failure modes. Methods Eighty molars' occlusal surfaces were ground to expose dentin and were randomly divided into 8 groups (n = 10): 1. Gluma (HEMA/Glutaraldehyde) 2. Bifluoride (Sodium Fluoride/Calcium Fluoride) 3. Admira (Bis-GMA/HEMA) 4. Smart Protect (Glutaraldehyde) 5. Teethmate (Tetracalcium phosphate, Dicalcium phosphate) 6. Clinpro White (Sodium fluoride) 7. BisBlock (Oxalic acid) and 8. Control (No-treatment). After applying the agent, a self-adhesive resin cement (Rely-X U200) was used to lute zirconia discs (4 mm height and 4 mm diameter) to dentin. After stored in distilled water at 37 degrees C for 24 h, all groups were thermocycled for 2500 cycles between 5 +/- 2 degrees C and 55 +/- 2 degrees C. Specimens were submitted to SBS test with a universal testing machine at a crosshead speed of 0.5 mm/min until failure. SBS values were compared with ANOVA. Post-hoc multiple comparisons were performed with Dunnett T3. The failure modes of specimens were examined with stereomicroscope at a magnification of 20X and the distribution of the failure modes were evaluated with Pearson Chi-Square test. Results Regarding mean SBS values in MPa's; Admira (10.70 +/- 3.99), Smart Protect (9.62 +/- 3.93), and Gluma (8.90 +/- 3.76) treatments showed higher SBS values compared to control group (p < .05) according to ANOVA. The SBS values of Teethmate (5.31 +/- 2.37) and Clinpro White (4.32 +/- 2.44) were higher than control group but the difference was not found significant (p > .05). BisBlock (2.33 +/- 1.94) and Bifluouride (1.60 +/- 1.47) groups showed the lowest SBS values but their difference between control group was not found statistically significant (p > .05). Most specimens showed adhesive failure but no statistically significant difference was found in the distributions of failure modes according to Chi-square test. Conclusion Within the limitation of the study; Admira, Smart Protect, and Gluma increased the SBS of the zirconia restorations to dentin and can be recommended to use on prepared dentin surfaces prior to the cementation.en10.1186/s12903-024-05106-8info:eu-repo/semantics/openAccessDentistryDesensitizersPost-operative hypersensitivityShear bond strengthArticle24119WOS:0013603893000032-s2.0-8520935701139563267Q2Q1