Çavuşoglu C.Çiçek Saydam C.Burhanoglu D.Özkalay N.Özkaya D.Özçam H.Bilgiç A.2019-10-272019-10-2720010374-90960374-9096https://hdl.handle.net/11454/23138In this study, the antibacterial activities of ofloxacin and ciprofloxacin on 100 clinical isolates of Mycobacterium tuberculosis were investigated by using standard proportion dilution method and E-test. The sensitivities of the isolates to conventional antibiotics (isoniazide, ethambutol, rifampin, streptomycin) were determined by Bactec system and 6 were found resistant to isoniazide, while 4 strains showed multi-drug resistance. All of the 10 resistant strains and 88 of 90 sensitive strains (98%) were found susceptible to ofloxacin and ciprofloxacin by both proportion dilution method and E-test. Two of the isolates (2%) which were susceptible to first choise antituberculous drugs, were found resistant to ofloxacin and ciprofloxacin by both of the methods. As a result, the accordance between E-test and standard proportion dilution method was detected as 100 percent.trinfo:eu-repo/semantics/closedAccessCiprofloxacinMycobacterium tuberculosisOfloxacinSusceptibilityArticle354505511Q4