Turkoglu M.Ozyar B.Kayaalti B.Ugur G.Nazli O.2019-10-272019-10-2719941016-51501016-5150https://hdl.handle.net/11454/24071In our study, we compared the effects of mannitol and furosemide on electrolyte balance and hemodynamic parameters in 20 patients undergoing TURP under spinal anaesthesia. We gave 80 g mannitol to ten patients and 40 mg furosemide to the others intravenously after the resection. Sodium concentration in both serum and urine and serum osmolarity are analysed in the samples taken before the operation, immediately after the prostatic resection, 1 hour, 4 hours and 24 hours after the operation. Heart rate, central venous pressure (CVP), systolic and diastolic arterial blood pressure were monitored and the patient's level of consciousness was observed during the operation. In the mannitol group, serum osmolarity decreased significantly in the samples, taken immediately after the resection, 4 and 24 hours after the operation. In the furosemide group urine sodium concentration increased significantly in the samples taken immediately after the resection and 1 hour after the operation. Systolic and diastolic arterial blood pressure, heart rate, CVP measurements ranged between normal limits in all patients. No patient showed any pathological sign of central nervous system disturbance. We conclude that both mannitol and furosemide can be used in order to prevent TUR syndrome and coagulum retention.trinfo:eu-repo/semantics/closedAccessFurosemideMannitolTUR syndromeArticle223171174N/A