Oztekin S.Gokpinar A.B.Akman H.Ugur G.Tutan A.2019-10-272019-10-2719941016-51501016-5150https://hdl.handle.net/11454/24073The aim of the study was to compare the influence of airway irritation upon oxygen saturation (SaO2) during halothane and isoflurane anaesthesia in children. Thirty unpremedicated children with ASA grades I and II were allocated randomly to receive either halothane or isoflurane. Heart rate and rhythm were monitored with an ECG and SaO2 was measured continuously with a pulse oximeter. The findings of the present study indicate that induction of anaesthesia with isoflurane may be prolonged and the irritant airway effects may interfere with the tissue oxygenation. In contrast, halothane produces rapid and smooth induction and SaO2 is usually not reduced. In conclusion, if isoflurane is used as an alternative to halothane for the induction of anaesthesia in unpremedicated children, a higher incidence of airway complications with associated decreases in SaO2 may result.trinfo:eu-repo/semantics/closedAccessHalothaneIsofluranePediatric anaesthesiaArticle2228183N/A