Ardic U.A.Ercan E.S.Ercan E.Yuce D.Basay B.K.2019-10-272019-10-2720141017-78331017-7833https://doi.org/10.5455/bcp.20141009112739https://hdl.handle.net/11454/26244Objective: The aim of this study was to evaluate the efficacy and safety of osmotic release oral system methylphenidate (OROS-MPH) compared with immediate release methylphenidate (IR-MPH) in Turkish children with attention deficit hyperactivity disorder (ADHD).Method: The medical records of primary school-aged children, who were first-time referrals to the outpatient clinic, were reviewed; 67 children receiving OROS-MPH and 47 children receiving IR-MPH were recruited for the study. A total of 114 children receiving treatment for ADHD were evaluated over 8 weeks.Results: The total Turgay DSM-IV Based Child and Adolescent Behavior Disorders Screening and Rating Scale scores from both the parent and teacher forms decreased significantly in both groups over 8 weeks (p<0.001). OROS-MPH was found to be superior to IR-MPH when comparing baseline-to-8th-week- mean inattention score changes on both the teacher (p=0.007) and parent (p=0.015) forms. OROS-MPH and IR-MPH were both well tolerated, with similar side- effect profiles.Conclusion: OROS-MPH was found to be effective and safe in the treatment of ADHD symptoms in Turkish children. © 2014, Cukurova Univ Tip Fakultesi Psikiyatri Anabilim Dali. All rights reserved.en10.5455/bcp.20141009112739info:eu-repo/semantics/closedAccessAttention deficit hyperactivity disorderChildrenMethylphenidateArticle244342349N/A