Aydogan, FadimeAli, ZulfiqarZulfiqar, FazilaKaraalp, CananKhan, Ikhlas A.Bedir, Erdal2024-08-252024-08-2520231874-39001876-7486https://doi.org/10.1016/j.phytol.2023.01.010https://hdl.handle.net/11454/102098Fifteen neo-clerodane diterpenoids (1-15), including two undescribed glycosides, teudivaricosides A (1) and B (2), together with a known iridoid glycoside (16) and a phenylpropanoid glycoside (17) from the whole plant of Teucrium divaricatum subsp. divaricatum were isolated. Their structures were determined by spectral data analysis including 1D and 2D NMR and HRESIMS. Neo-clerodane diterpenoids were evaluated for their anti-inflammatory, and antimicrobial activities. None of them showed significant antimicrobial activity against various bacterial and fungal strains (up to 20 mu g/mL). All tested compounds were inactive up to the highest tested concentration of 50 mu M on iNOS inhibitory activity.en10.1016/j.phytol.2023.01.010info:eu-repo/semantics/closedAccessTeucrium divaricatum subspdivaricatumLamiaceaeneo-clerodaneAntimicrobialiNOSNeoclerodane DiterpenoidsFuranoid DiterpenesChamaedrysPhytochemistryGlucosideC-12Article544549WOS:0009633922000012-s2.0-85146858756Q2Q3