Darcan, SAkisu, MTaneli, BKendir, G2019-10-272019-10-2719960009-9163https://hdl.handle.net/11454/35079Pycnodysostosis is a skeletal dysplasia characterized by short stature. Treatment of pycnodysostosis with growth hormone (GH) has not been reported so far. We describe a case of pycnodysostosis with growth hormone deficiency in addition to low mean insulin-like growth factor 1 (IGF-1) concentration. Complete GH deficiency was determined by two pharmacological provocative tests (insulin and L-dopa). A good height velocity response was obtained after GH replacement treatment. Pycnodysostosis with GH deficiency and replacement therapy have not been reported previously, to the best of our knowledge.eninfo:eu-repo/semantics/closedAccessbonesdysostosesgrowth hormonepycnodysostosisArticle505422425WOS:A1996VZ935000269007336Q1N/A