Kocaturk, TolgaErkan, ErolEgrilmez, SaitCakmak, HarunDundar, Sema O.Dayanir, Volkan2019-10-272019-10-2720151874-3641https://doi.org/10.2174/1874364101509010121https://hdl.handle.net/11454/49339Purpose: To evaluate surgically induced astigmatism (SIA) after an intravitreal ranibizumab (IVR) injection. Methods: Fifty eight eyes of 58 patients who underwent IVR injection due to age-related macular degeneration (wet form) or macular edema were included in this study. Patients' pre-and postoperative detailed ophthalmologic examinations were done and topographic keratometric values (K1, K2) were noted. Pre- and postoperative measurements were compared. Results: The mean preoperative astigmatism of 0.87 Diopters (D) was found to be 0.95 D, 0.75 D, 0.82 D and 0.78 D on the 1st day, 3rd day, 1st week and 1st month, respectively. After injection, absolute change in astigmatism was found to be 0.08 D, 0.12 D, 0.05 D and 0.09 D on the 1st day, 3rd day, 1st week and 1st month, respectively. The absolute change in astigmatism seemed to be insignificant in terms of refractive analysis, however; when we performed a vectorial analysis, which takes into account changes in the axis of astigmatism, the mean value of induced astigmatism were found to be 0.33 +/- 0.22 D, 0.32 +/- 0.29 D, 0.41 +/- 0.37 D, 0.46 +/- 0.32 D on the 1st day, 3rd day, 1st week and on 1st month, respectively. Conclusion: Intravitreal injection is a minimally invasive ophthalmologic procedure, however; it may still cause statistically significant induced astigmatism when evaluated from a vectorial point of view.en10.2174/1874364101509010121info:eu-repo/semantics/openAccessIntraocular pressureintravitreal injectionranibizumabsurgically induced astigmatismvectorial analysisArticle9121125WOS:00042458440001426401170N/A