Kalfa, MelikeKocanaogullari, HayriyeZihni, Figen YargucuKarabulut, GoncaEmmungil, HakanInal, Vedat2019-10-272019-10-2720152147-97202148-4279https://doi.org/10.5152/eurjrheum.2015.0004https://hdl.handle.net/11454/51714Scleredema is a rare connective tissue disorder of unknown pathogenesis. Three types of scleredema have been described, based on its association with postinfection, monoclonal gammopathy and diabetes mellitus. We report herein a case of scleredema which the diagnosis didn't get specified. The patient was followed regularly for 13 years and did not respond to various combinations of immuno-suppressants and psoralen plus ultraviolet A therapy. Treatment of scleredema is quite difficult and of limited success. At present, there is no proved treatment for this disease.en10.5152/eurjrheum.2015.0004info:eu-repo/semantics/openAccessScleredemamethotrexatePUVAArticle24163+WOS:00036558710000827708956N/A