Ertay T.Ünak P.Özdogan O.Biber F.Z.Zihnioglu F.Medine E.I.Durak H.2019-10-272019-10-2720060236-57310236-5731https://doi.org/10.1007/s10967-006-0226-2https://hdl.handle.net/11454/27655A glucuronide derivative of exorphin C called exorphin C glucuronide was obtained by enzymatic synthesis and labeled with 99mTc using glucoheptonate (GH) as bifunctional chelating agent. Labeling efficiency was 99.7±0.03%. Biodistribution studies were performed on normal and mammary tumor bearing albino Wistar rats. In addition, scintigraphic imaging with 99mTc-GH-exorphin C glucuronide (99mTc-GEG) was performed. The radiopeptide-glucuronide is rapidly cleared via the urinary system showing lower liver uptake. Results demonstrated that 99mTc-GEG can be used as a vehicle to target tumors. © 2006 Akadémiai Kiadó.en10.1007/s10967-006-0226-2info:eu-repo/semantics/closedAccessArticle26912128Q2