Kurugol Z.Ozsacar T.Egemen A.Arcasoy M.Yenigun A.Bilgic A.2019-10-272019-10-2719951300-01441300-0144https://hdl.handle.net/11454/24030In Turkey, two measles outbreaks occurred in 1989 and 1993. The majority of cases has been previously vaccinated children. We evaluated the necessity of measles revaccination in 4-7-year-old children by establishing the increase in anti-measles IgG level following revaccination, and by determining the percentage of measles-susceptible subjects in previously vaccinated children. Seventy-five children were revaccinated and sera were collected just prior to revaccination and after two weeks. Anti-measles IgG titers were determined by enzyme immunoassay. Four-fold and greater increases in anti-measles IgG titers were obtained in 17.3% of children, and they were defined as immunologically susceptible to measles. Pre-revaccination measles specific IgG titers less than 3224 ng/ml were a significant risk factor for measles susceptibility. None of the revaccinated children had notable complications. These data support the necessity and safety of measles revaccination.eninfo:eu-repo/semantics/closedAccessimmunizationmeasles antibodiesmeasles vaccineArticle2515155Q3