Ertay, T.Unak, P.Ozdogan, O.Biber, F. Z.Zihnioglu, F.Medine, E. I.Durak, H.2019-10-272019-10-2720060236-57310236-5731https://doi.org/10.1007/s10967-006-0226-2https://hdl.handle.net/11454/38519A glucuronide derivative of exorphin C called exorphin C glucuronide was obtained by enzymatic synthesis and labeled with Tc-99m using glucoheptonate (GH) as bifunctional chelating agent. Labeling efficiency was 99.7 +/- 0.03%. Biodistribution studies were performed on normal and mammary tumor bearing albino Wistar rats. In addition, scintigraphic imaging with Tc-99m-GH-exorphin C glucuronide (Tc-99m-GEG) was performed. The radiopeptide-glucuronide is rapidly cleared via the urinary system showing lower liver uptake. Results demonstrated that Tc-99m-GEG can be used as a vehicle to target tumors.en10.1007/s10967-006-0226-2info:eu-repo/semantics/closedAccessArticle26912128WOS:000239298600004Q3