Akbulut, HuseyinYavuz, MuratGuler, EmineDemirkol, Dilek OdaciEndo, TakeshiYamada, ShuheiTimur, SunaYagci, Yusuf2019-10-272019-10-2720141759-99541759-99621759-99541759-9962https://doi.org/10.1039/c4py00079jhttps://hdl.handle.net/11454/48642A simple and efficient approach for the electrochemical deposition of polypeptides as bio-based covering materials for surface design is described. The method involves N-carboxyanhydride (NCA) ring-opening polymerization from its precursor to form a thiophene-functionalized polypeptide macromonomer (T-Pala), followed by electropolymerization. The obtained conducting polymer, namely polythiophene-g- polyalanine (PT-Pala), was characterized and utilized as a matrix for biomolecule attachment. The biosensing applicability of PT-Pala was also investigated by using glucose oxidase (GOx) as a model enzyme to detect glucose. The designed biosensor showed a very good linearity for 0.01-1.0 mM glucose. Finally, the antimicrobial activities of newly synthesized T-Pala and PT-Pala were also evaluated by using the disc diffusion method.en10.1039/c4py00079jinfo:eu-repo/semantics/closedAccessArticle51239293936WOS:000336804800024Q1Q1