Kocagozoglu, GamzeLambrecht, Fatma YurtGunduz, CumhurYucebas, MusteydeTabar, Elif BayrakOzgur, AykutBalci, Tugce2019-10-272019-10-2720110969-8043https://doi.org/10.1016/j.apradiso.2011.03.006https://hdl.handle.net/11454/44315Radiopharmaceuticals are useful to evaluate effectiveness of cancer treatments as well as diagnosis of diseases. Tc-99m-Glucoheptonate has high sensitivity for imaging lung cancer tissues. In this study, the potential use of Tc-99m-glucoheptonate for monitoring apoptosis related to chemotherapeutic agents is investigated in vitro using A549 lung cancer cell line. A decrease in Tc-99m-glucoheptonate uptake ratio was observed depending on the level of apoptosis. Tc-99m-glucoheptonate is found to be useful for the detection of apoptosis following treatment in A549 lung tumor cells. (C) 2011 Elsevier Ltd. All rights reserved.en10.1016/j.apradiso.2011.03.006info:eu-repo/semantics/closedAccessApoptosisCancerTc-99mTc-99m-glucoheptonateArticle697955959WOS:00029145630000721459007Q2