Sakarya M.Ulukaya E.Cevik A.Moral A.R.2019-10-272019-10-2719971016-51501016-5150https://hdl.handle.net/11454/23761In this study, the effects of dobutamine infusion, given at 3 µg/kg/min and 6 µg/kg/min, on oxygen consumption (VO2) and energy expenditure (EE) were evaluated in ten nonseptic and ten septic patients. Each dose of dobutamine was infused for 30 minutes. All patients were monitorized with both a radial artery and a pulmonary artery catheter. Cardiac output was measured using thermodilution technique. VO2 and EE were calculated before debutamine infusion as control, and at the end of each dose dobutamine infusion. The mean EE of control, after 3 µg/kg/min and 6 µg/kg/min of dobutamine were 1850±108, 2086±157, 2067±100 kcal/day, respectively, in nonseptic patients; 1781±104, 1905±103, 1985±101 kcal/day, respectively, in septic patients. Compared with control measurements, EE increased by 11% in response to maximum dose of dobutamine infusion in two groups. There were no differences between the nonseptic and septic patients. We conclude that the additional energy demands imposed by dobutamine infusion needs to be taken into account to determine the energy requirements of critically ill patients.trinfo:eu-repo/semantics/closedAccessDobutamineEnergy expenditureOxygen consumptionArticle258348351N/A