Gozler B.Gunes H.S.Hesse M.2019-10-272019-10-2719951015-95921015-9592https://hdl.handle.net/11454/24026(A-)-4,4',9-trihydroxy-3,3'-dimethoxy-9,9' epoxylignan (1), a 9,9'-epoxylignan encompassing a rather rarely encountered dibenzylbutyrolactol structure, has been isolated from Haplophyllum cappadocicum (Rutaceae) of Turkish origin. Since 1 is so far reported only from a Pinus species, this is the first isolation of this compound from the Rutaceae. The title plant also afforded (-)-tuberculatin (4), a b-D apioside of diphyllin, which has been isolated previously from two other Haplophyllum species, suggesting that this glycoside may be a common element of the Haplophyllum genus. Structure elucidation was done by extensive spectral analyses.eninfo:eu-repo/semantics/closedAccess% lignansdibenzylbutyrolactolsdiphyllin b-D-apiosideepoxylignansHaplophyllumHaplophyllum cappadocicumlignan glycosidestuberculatinArticle121915N/A