Uyanikgil Y.Ateş U.Baka M.Biçer S.Öztaş E.Ergen G.2019-10-272019-10-2720090007-4861https://doi.org/10.1007/s00128-009-9689-5https://hdl.handle.net/11454/27287This study aims to investigate the effect of 2,4-dichlorophenoxyacetic acid (2,4-D) on rat kidney cortex histology. Oral exposure of rats to 2,4-D for 28 days resulted in decreases in body weight gain and kidney weight. Histological examination showed degeneration in renal corpuscles and podocytes; vacuolization in the glomerulus with disintegration of the basal membrane; tissue edema; vacuolization, cystic dilation and invagination of the basal laminae in the tubular structures; dilation and congestion in renal corpuscular vessels and marked decrease in glomerular and stromal fibronectin reaction; suggesting that subacute 2,4-D administration induces dose-dependent histopathological degenerative effects in rat kidney cortex. © 2009 Springer Science+Business Media, LLC.en10.1007/s00128-009-9689-5info:eu-repo/semantics/closedAccess2,4-DHerbicideHistopathologyKidneyRatArticle82674975519277441Q2