Aktan E.Bozkurt K.Ozer D.Yucebilgin S.Karadadas N.Bilgin O.2019-10-272019-10-2720040004-8666https://doi.org/10.1111/j.1479-828X.2004.00226.xhttps://hdl.handle.net/11454/22547Objectives: To determine the effects of 'coasting' on the outcome of controlled ovarian hyperstimulation (COH) and intracytoplasmic sperm injection-embryo transfer (ICSI-ET). Design: Retrospective study. Setting: IVF Centre, Ozel Ege Tup Bebek Merkezi, Izmir, Turkey. Sample: Twenty-six coasted and 52 non-coasted COH and ICSI-ET patients were enrolled in this retrospective study. Methods: Coasted patients were enrolled consecutively during the study period, and two non-coasted controls were selected from our database for each coasted patient. Coasting was decided when serum oestradiol level was ?4000 pg/mL. Groups were compared using x2 and Mann-Whitney U-tests for statistical analysis. Main Outcome Measures: Number of oocytes collected, metaphase II (MII) oocytes and cleaving embryos, the fertilisation rate and clinical pregnancy rate were the main outcome measures. Results: Number of oocytes collected, number of MII oocytes, number of cleaving embryos, fertilisation rate and clinical pregnancy rate for the coasted and non-coasted groups were 15.5 ± 5.2 and 14.0 ± 7.1, 9.7 ± 4.8 and 9.3 ± 3.9, 6.8 ± 3.9 and 5.8 ± 3.1, 0.85 ± 0.18 and 0.78 ± 0.18, 13/26 and 24/52, respectively; these differences were not statistically significant. None of the patients in the coasted group were hospitalised for signs or findings of severe ovarian hyperstimulation syndrome. Conclusions: Coasting does not adversely affect the number and the function of mature oocytes and the clinical pregnancy rate.en10.1111/j.1479-828X.2004.00226.xinfo:eu-repo/semantics/closedAccessCoastingIntracytoplasmic sperm injectionOutcomeOvarian hyperstimulation syndromeArticle44429830115281999N/A