Yildirim, YelizTelli, FatmaKahraman, ErkanGardiner, John M.2024-08-252024-08-2520231385-772X1568-5551https://doi.org/10.1080/15685551.2023.2199506https://hdl.handle.net/11454/101722The synthesis of glycopolymers by copolymerising an allyl glucosamine (AG) monomer with co-monomers methyl methacrylate (MMA), acrylonitrile (AN) and 2-hydroxyethyl methacrylate (HEMA) was investigated via free-radical polymerisation of 2,2-azobisisobutyronitrile (AIBN) in dimethylformamide (DMF). Three new copolymers, poly(AG-co-MMA), poly(AG-co-AN) and poly(AG-co-HEMA), were obtained. The chemical structures of the glycopolymers were analysed using H-1-NMR, C-13-NMR and FTIR. The thermal properties and degradation kinetics of the three glycopolymers were examined by thermogravimetric (TG) analysis at different heating rates. The effects of different co-monomers on the copolymerisation yield, thermal properties and biological activities of the resulting glycopolymers were investigated. The activation energies of the decomposition stages were calculated using the Flynn-Wall-Ozawa (FWO) and Kissinger methods. Furthermore, the biological activity of AG monomers and glycopolymers was studied and compared to chitosan. Poly(AG-co-HEMA) had the most significant effect on MCF-7 cell viability, and all glycopolymers have a low toxic effect profile on MCF-7 cell lines.en10.1080/15685551.2023.2199506info:eu-repo/semantics/closedAccessGlycopolymerscarbohydrate-based allyl copolymerdecomposition kineticthermal analysisbiological applicationsThermal-DegradationChitosanCopolymersPolymerizationAcrylonitrilePolymersPolyacrylonitrileDerivativesBiopolymerMembranesArticle261117131WOS:0009693656000012-s2.0-8515276897637064216Q2Q3