Sengiz C.Congur G.Eksin E.Erdem A.2019-10-262019-10-2620151040-03971040-0397https://doi.org/10.1002/elan.201500107https://hdl.handle.net/11454/17129A multiwalled carbon nanotubes (CNT)-chitosan (CHIT) modified pencil graphite electrode (CNT-CHIT/PGE) was developed for the first time herein for electrochemical monitoring of the interaction of an anticancer drug, mitomycin C (MC) and DNA. The characterization of unmodified PGE, CHIT/PGE, CNT/PGE and CHIT-CNT/PGE were performed by scanning electron microscopy and cyclic voltammetry techniques. The oxidation signals of MC and guanine were measured before and after interaction at the surface of CNT-CHIT/PGEs using differential pulse voltammetry. Electrochemical impedance spectroscopy technique was also successfully utilized for monitoring of the interaction process at the surface of CNT-CHIT/PGEs in different interaction times. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.en10.1002/elan.201500107info:eu-repo/semantics/closedAccessChitosanDrug-DNA interactionsElectrochemical biosensorsMitomycin CMultiwalled carbon nanotubesArticle27818551863Q2