Uyar M.Uyar M.Ugur G.Mert S.Ozyar B.Ozyurt C.2019-10-272019-10-2719981300-00121300-0012https://hdl.handle.net/11454/23572We evaluated patient-controlled administration of alfentanil(PCA group) as an alternative to conventional intermittent injection technique(standard treatment group) in 40 patients undergoing extracorporeal shock wave lithotripsy (ESWL) of urinary tract calculi. After a loading dose of alfentanil (10 µg/kg) in both groups, standard treatment patients were given 5 µg/kg of alfentanil in as needed fashion. Patients using patient controlled analgesia (PCA) were allowed to self-administer 100 µg of alfentanil intravenously with a lockout interval of 5 min and 900 µg/h maintenance infusion. The two alfentanil administration techniques were equally effective in providing analgesia during the procedure. PCA patients used less alfentanil than the standard treatment group (2414±510 µg vs 3220±700 µg, respectively, p<0.05). Pain and sedation scores were comparable between the two groups. There were no significant hemodynamic differences between the two groups. Standard treatment patients had significantly lower respiratory rates and a higher oxygen desaturation episodes. Two patients in this group developed bradypnea(<10 breaths/min). Administration of alfentanil with PCA during ESWL reduces opioid requirements thus increases the safety of the procedure while providing adequate analgesia.eninfo:eu-repo/semantics/closedAccessAlfentanilExtracorporeal shock wave lithotripsyPatient controlled analgesiaArticle1033741Q3