Palamar, MelisEgrilmez, SaitYilmaz, Suzan GuvenPolat, Suleyha HilmiogluGunduz, Omur Ucakhan2019-10-272019-10-2720151120-009X1973-9478https://doi.org/10.1179/1973947814Y.0000000166https://hdl.handle.net/11454/50861Purpose: Systemic voriconazole treatment was reported to cause photosensitivity and related cutaneous malignancies. The aim of this report is to demonstrate a graft-related Candida endophthalmitis case that developed ocular surface dysplastic changes after receiving topical 1% voriconazole treatment. Methods: Full ocular examination, photography, and in vivo confocal microscopy examination (Rostock Cornea Module/HRT II, Heidelberg, Germany) were performed. Results: A 73-year-old male with graft-related Candida endophthalmitis that was on topical 1% voriconazole for 4 months developed a whitish gelatinous lesion on the cornea originating from the nasal limbus. In vivo confocal microscopy examination revealed mild dysplastic changes in the cornea epithelium. Conclusion: Topical voriconazole might trigger neoplastic changes on the ocular surface as reported with systemic use in other sun-exposed parts of the body. Further studies are needed to relate topical use of voriconazole with ocular surface dysplasia.en10.1179/1973947814Y.0000000166info:eu-repo/semantics/closedAccessCandidaConfocal microscopyCorneaDysplasiaPenetrating keratoplastyVoriconazoleArticle272111113WOS:00035106070000924621171Q3Q4