Deri kanserlerinde radyoterapi sonrası kozmetik sonuç
Küçük Resim Yok
Tarih
2001
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Deri kanserlerinin çoğu iyonizan radyasyona duyarlı olup, çevre normal doku tarafından iyi tolere edilebilen dozlarla tedavi sağlanabilmektedir. Yüzeyel x ışını tedavisi doğru şekilde uygulandığında büyük tümörlerde bile şekil ve fonksiyon bozukluğu oluşturmaksızın ve sonradan rekonstrüktif cerrahi girişim gerektirmeksizin seçici hasar oluşturabilmektedir. Bu çalışma yüzeyel x ışını tedavisinden sonra kozmetik sonuçları değerlendirmek amacıyla yapılmıştır. Çalışmaya toplam 121 lezyonlu 100 hasta dahil edilmiştir. Histopatolojik olarak lezyonların 89'u bazal hücreli, 26'sı skuamöz hücreli, 4'ü intraepidermik epitelyomalı, 2'si de bazoskuamöz hücreli karsinom yapısındaydı. Tüm lezyonlar yüzeyel bir x ışını cihazı ile ışınlandılar (voltaj:100 kV, şiddet:10 mA). Total doz 4200-6000 cGy arasında değişmekteydi. Hastalar toplam 5 yıl süre için klinik şifa yanısıra şekil ve fonksiyon bozukluğu ile radyodermatit açısından değerlendirildiler. Tedavi sonunda 3 lezyon alopesi, 6 lezyonda gelişen kronik radyodermatit bulguları nedeniyle olmak üzere toplam 9 lezyon (%7,7) kötü kozmetik sonuç olarak değerlendirildi. Diğer lezyonlarda (%92,3) tedavi sonucu iyileşme, kozmetik olarak kabul edilebilir özellikte bulundu. Sonuç olarak yüzeyel x ışını tedavisi deri kanserlerinde uygun ve kozmetik bir tedavi yöntemi olarak değerlendirildi.
Background and design: Most cutaneous cancers are sensitive to ionizing radiation and can be treated by doses that are well tolerated by the surrounding normal tissue. Superficial x-ray therapy, when skillfully applied, can result in the selective destruction of even large tumors without mutilation or dysfunction and without the need for subsequent reconstructive surgical procedures. the purpose of this study was to evaluate the cosmetic results after superficial x-ray therapy. Material and methods: A total of 100 patients with 121 skin cancers were included in this study. AlI the lesions were irradiated with a superficial x-ray device (voltage:100 kV, intensity:10 mA). Total dose of radiation changed between 4200 and 6000 cGy. Patients were examined clinically for mutilation, dysfunction, recurrence, radiodermatitis and clinical cure for a period of five years. Results: Histopathologically, of all the lesions, 89 were basal cell carcinomas, 26 were squamous cell carcinomas, 4 were intraepidermal epitheliomas and two were basosquamous cell carcinomas. While 6 lesions revealed radiodermatitis findings, 3 lesions had hair loss after radiotherapy. As a result, these nine lesions (7,7%) were accepted as bad long-term cosmetic outcome. Cosmetic results were found highly acceptable for most of the lesions (92,3%) at the end of the treatment. Conclusion: Superficial x-ray therapy is a suitable and cosmetic modality for skin carcinomas
Background and design: Most cutaneous cancers are sensitive to ionizing radiation and can be treated by doses that are well tolerated by the surrounding normal tissue. Superficial x-ray therapy, when skillfully applied, can result in the selective destruction of even large tumors without mutilation or dysfunction and without the need for subsequent reconstructive surgical procedures. the purpose of this study was to evaluate the cosmetic results after superficial x-ray therapy. Material and methods: A total of 100 patients with 121 skin cancers were included in this study. AlI the lesions were irradiated with a superficial x-ray device (voltage:100 kV, intensity:10 mA). Total dose of radiation changed between 4200 and 6000 cGy. Patients were examined clinically for mutilation, dysfunction, recurrence, radiodermatitis and clinical cure for a period of five years. Results: Histopathologically, of all the lesions, 89 were basal cell carcinomas, 26 were squamous cell carcinomas, 4 were intraepidermal epitheliomas and two were basosquamous cell carcinomas. While 6 lesions revealed radiodermatitis findings, 3 lesions had hair loss after radiotherapy. As a result, these nine lesions (7,7%) were accepted as bad long-term cosmetic outcome. Cosmetic results were found highly acceptable for most of the lesions (92,3%) at the end of the treatment. Conclusion: Superficial x-ray therapy is a suitable and cosmetic modality for skin carcinomas
Açıklama
Anahtar Kelimeler
Dermatoloji
Kaynak
Türkderm-Deri Hastalıkları ve Frengi Arşivi
WoS Q Değeri
Scopus Q Değeri
Cilt
35
Sayı
3
